51146-36-2

Basic information

• Product Name: aci-nitroethane trimethylsilyl ester
• CAS NO: 51146-36-2
• Molecular Weight: 147.249
• Mol File: 51146-36-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: aci-nitroethane trimethylsilyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: aci-nitroethane trimethylsilyl ester(51146-36-2)
• EPA Substance Registry System: aci-nitroethane trimethylsilyl ester(51146-36-2)

Safety Data

• Hazardous Substances Data: 51146-36-2(Hazardous Substances Data)

Upstream product

• 1660-94-2 Tetraethyl methylenediphosphonate 
• 52287-58-8 1-(2,4-Dichlorphenyl)-2-nitropropen 
• 52287-57-7 2-nitro-1-(4'-dimethylaminophenyl)-1-propene 
• 4231-16-7 1-(p-nitrophenyl)-2-nitro-1-propene 
• 710-20-3 1-chloro-4-(2-nitropropenyl)benzene 
• 17354-63-1 4-(2-nitro-propenyl)-anisole 
• 705-60-2 (2-nitroprop-1-enyl)benzene 

Downstream Products

• 66376-18-9 1-Phenyl-2-nitropropyl-trimethylsilylaether 
• 17492-61-4 1-(3-methyl-4,5-dihydro-isoxazol-5-yl)-ethanone 

Relevant articles and documents

STUDIES ON ORGANOPHOSPHORUS COMPOUNDS 62. REACTIONS OF METHYLENEBISPHOSPHONATE WITH α-NITROALKENES. A NOVEL SYNTHESIS OF ETHENYLIDENEBISPHOSPHONATES AND 2-ISOXAZOLINE-5,5-DIYLBISPHOSPHONATES

Reaction of methylenebisphosphonate with α-nitroalkenes followed by addition of trimethylchlorosilane leads to the formation of ethenylidenebisphosphonates and trimethylsilyl nitronate in almost quantitative yield.These two products, upon prolonged reaction at ambient temperature, provide 2-isoxazoline-5,5-diylbisphosphonates via regioselective 1,3-dipolar cycloaddition in high yield.Key words: Methylenebisphosphonate; α-nitroalkenes; ethenylidenebisphosphonate; 2-isoxazoline-5,5-diylbisphosphonate; 1,3-dipolar cycloaddition.