5115-75-3

Basic information

• Product Name: (1S,4aS,8aR)-4a-hydroxy-1-(3,4,5-trimethoxyphenyl)decahydroisoquinolinium chloride
• CAS NO: 5115-75-3
• Molecular Formula: C₁₈H₂₈ClNO₄
• Molecular Weight: 357.8722
• Mol File: 5115-75-3.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 452.1°C at 760 mmHg
• Flash Point: 227.2°C
• Vapor Pressure: 5.79E-09mmHg at 25°C
• CAS DataBase Reference: (1S,4aS,8aR)-4a-hydroxy-1-(3,4,5-trimethoxyphenyl)decahydroisoquinolinium chloride(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,4aS,8aR)-4a-hydroxy-1-(3,4,5-trimethoxyphenyl)decahydroisoquinolinium chloride(5115-75-3)
• EPA Substance Registry System: (1S,4aS,8aR)-4a-hydroxy-1-(3,4,5-trimethoxyphenyl)decahydroisoquinolinium chloride(5115-75-3)

Safety Data

• Hazardous Substances Data: 5115-75-3(Hazardous Substances Data)

Usage

General Description

The chemical (1S,4aS,8aR)-4a-hydroxy-1-(3,4,5-trimethoxyphenyl)decahydroisoquinolinium chloride, also known as (R)-Nantenine, is a naturally occurring alkaloid found in several plant species. It is classified as an isoquinoline alkaloid and has been isolated from Nandina domestica, a plant commonly known as heavenly bamboo. (R)-Nantenine has been studied for its potential pharmacological activities, including its anti-inflammatory, analgesic, and antioxidant properties. It has also been investigated for its potential in the treatment of cardiovascular and neurological disorders. The compound's structure and pharmacological effects make it an interesting target for further research and potential therapeutic applications.

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Relevant articles and documents

UGT74B1 from Arabidopsis thaliana as a versatile biocatalyst for the synthesis of desulfoglycosinolates

Thioglycosides, even if rare in Nature, have gained increased interest for their biological properties. Chemical syntheses of this class of compounds have been largely studied but little has been reported on their biosynthesis. Herein, combining experiments from the different fields of enzymology, bioorganic chemistry and molecular modeling, we wish to demonstrate the versatility of the glucosyltransferase UGT74B1 and its synthetic potency for the preparation of a variety of natural and unnatural desulfoglycosinolates.