511533-38-3

Basic information

• Product Name: 5-Iodo-1-Indanone
• Synonyms: 5-Iodo-1-Indanone;2,3-dihydro-5-iodoinden-1-one;5-Iodoindan-1-one;2,3-Dihydro-5-iodo-1H-inden-1-one, 2,3-Dihydro-5-iodo-1-oxo-1H-indene;5-Iodo-2,3-dihydro-1H-inden-1-one;2,3-Dihydro-5-iodo-1H-inden-1-one;5-iodo-2,3-dihydroinden-1-one
• CAS NO: 511533-38-3
• Molecular Formula: C₉H₇IO
• Molecular Weight: 258.05575
• EINECS: 604-604-1
• Mol File: 511533-38-3.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 326℃
• Flash Point: 151℃
• Appearance: /
• Density: 1.882
• Vapor Pressure: 0.000224mmHg at 25°C
• Refractive Index: 1.674
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• CAS DataBase Reference: 5-Iodo-1-Indanone(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Iodo-1-Indanone(511533-38-3)
• EPA Substance Registry System: 5-Iodo-1-Indanone(511533-38-3)

Safety Data

• Hazardous Substances Data: 511533-38-3(Hazardous Substances Data)

Usage

General Description

5-Iodo-1-indanone is a chemical compound with the molecular formula C9H7IO. It is a yellow crystalline solid and is commonly used as a reagent in organic synthesis. 5-Iodo-1-Indanone is a derivative of indanone, which is a building block for many other organic compounds. 5-Iodo-1-indanone is often used in the pharmaceutical industry for the synthesis of various drugs and drug intermediates. It is also used as a precursor for the synthesis of other iodine-containing organic compounds. This chemical has potential applications in the field of medicinal chemistry and drug discovery.

InChI:InChI=1/C9H7IO/c10-7-2-3-8-6(5-7)1-4-9(8)11/h2-3,5H,1,4H2

Upstream product

• 3470-54-0 5-aminoindan-1-one 

Downstream Products

• 511533-10-1 1-(2',4'-dichlorophenyl)-6-iodo-1,4-dihydroindeno[1,2-c]pyrazole-3-carboxylic acid 
• 511533-22-5 ethyl 1-(2',4'-dichlorophenyl)-6-iodo-1,4-dihydroindeno[1,2-c]pyrazole-3-carboxylate 
• 869725-57-5 5-(trifluoromethyl)-2,3-dihydro-1H-inden-1-ol 
• 150969-56-5 5-(trifluoromethyl)-2,3-dihydro-1H-inden-1-one 

Relevant articles and documents

Synthesis of haloindenes

The subject invention provides an expedited synthesis of 5, 6, and 7-iodoindenes from the corresponding aminoindan-1-ones in more than 70% yield, employing readily available precursors and reagents. A three-step sequence involves diazotization-iodination of aminoindan-1-one followed by reduction and dehydration. The method has a general character and can be extended for the preparation of various 4-, 5-, 6- or 7-haloindenes using different halogen sources for diazotization-halogenation reaction.

CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE

Described herein are compounds, methods of making such compounds, pharmaceutical compositions and medicaments containing such compounds, and methods of using such compounds to treat or prevent diseases or disorders associated with the enzyme ceramide galactosyltransferase (CGT), such as, for example, lysosomal storage diseases. Examples of lysosomal storage diseases include, for example, Krabbe disease and Metachromatic Leukodystrophy.