51207-98-8

Basic information

• Product Name: N-n-Butyl-4-nitrobenzaMide, 97%
• Synonyms: N-n-Butyl-4-nitrobenzaMide, 97%
• CAS NO: 51207-98-8
• Molecular Formula: C₁₁H₁₄N₂O₃
• Molecular Weight: 222.24046
• Mol File: 51207-98-8.mol
• Article Data: 32

Chemical Properties

• Boiling Point: 404.8°C at 760 mmHg
• Flash Point: 198.6°C
• Appearance: /
• Density: 1.162g/cm³
• Vapor Pressure: 9.21E-07mmHg at 25°C
• Refractive Index: 1.543
• CAS DataBase Reference: N-n-Butyl-4-nitrobenzaMide, 97%(CAS DataBase Reference)
• NIST Chemistry Reference: N-n-Butyl-4-nitrobenzaMide, 97%(51207-98-8)
• EPA Substance Registry System: N-n-Butyl-4-nitrobenzaMide, 97%(51207-98-8)

Safety Data

• Hazardous Substances Data: 51207-98-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C11H14N2O3/c1-2-3-8-12-11(14)9-4-6-10(7-5-9)13(15)16/h4-7H,2-3,8H2,1H3,(H,12,14)

Upstream product

• 122-04-3 4-nitro-benzoyl chloride 
• 109-73-9 N-butylamine 
• 1037-31-6 4-nitrophenyl 4-nitrobenzoate 
• 6465-01-6 (4-nitrophenyl)carbamic acid phenyl ester 
• 61081-80-9 p-nitrobenzoate de cyclopentyle 
• 37844-60-3 p-nitrobenzoate d'hydroxy-2 cyclopentyle cis 
• 37844-60-3 p-nitrobenzoate d'hydroxy-2 cyclopentyle trans 
• 62-23-7 4-nitro-benzoic acid 
• 555-16-8 4-nitrobenzaldehdye 
• 619-73-8 4-nitrobenzyl chloride 
• 636-98-6 p-nitrobenzene iodide 
• 201230-82-2 carbon monoxide 
• 13939-06-5 molybdenum hexacarbonyl 
• 100-19-6 (4-nitrophenyl)ethanone 

Downstream Products

• 51207-84-2 4-amino-N-butylbenzamide 
• 1417547-08-0 N-(4-(n-butylcarbamoyl)phenylcarbamoyl)-2,6-difluorobenzamide 

Relevant articles and documents

Novel Conjugated s-Tetrazine Derivatives Bearing a 4H-1,2,4-Triazole Scaffold: Synthesis and Luminescent Properties

A series of new symmetrical s-tetrazine derivatives, coupled via a 1,4-phenylene linkage with a 4H-1,2,4-triazole ring, were obtained. The combination of these two rings in an extensively coupled system has significant potential applications, mainly in op

N -Heterocyclic carbene (NHC) catalyzed amidation of aldehydes with amines via the tandem N -hydroxysuccinimide ester formation

A facile method for the amidation of aldehydes by a cascade approach was developed. This methodology, reported for the first time, uses a N-heterocyclic carbene (NHC) as the catalyst, and N-hydroxysuccinimide (NHS) mediated synthesis of amides utilising TBHP as the oxidant. Various substituted aldehydes reacted smoothly with NHS giving the corresponding active esters in moderate to good yields, which facilely converted into amides in one pot. In addition, the drug moclobemide was synthesized to represent the practical utility of the developed methodology. This journal is

A CO2-Catalyzed Transamidation Reaction

Transamidation reactions are often mediated by reactive substrates in the presence of overstoichiometric activating reagents and/or transition metal catalysts. Here we report the use of CO2as a traceless catalyst: in the presence of catalytic amounts of CO2, transamidation reactions were accelerated with primary, secondary, and tertiary amide donors. Various amine nucleophiles including amino acid derivatives were tolerated, showcasing the utility of transamidation in peptide modification and polymer degradation (e.g., Nylon-6,6). In particular,N,O-dimethylhydroxyl amides (Weinreb amides) displayed a distinct reactivity in the CO2-catalyzed transamidation versus a N2atmosphere. Comparative Hammett studies and kinetic analysis were conducted to elucidate the catalytic activation mechanism of molecular CO2, which was supported by DFT calculations. We attributed the positive effect of CO2in the transamidation reaction to the stabilization of tetrahedral intermediates by covalent binding to the electrophilic CO2