51217-59-5

Basic information

• Product Name: 5-Chlor-2-amino-4'-methoxy-benzophenon-oxim
• CAS NO: 51217-59-5
• Molecular Weight: 276.722
• Mol File: 51217-59-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-Chlor-2-amino-4'-methoxy-benzophenon-oxim(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Chlor-2-amino-4'-methoxy-benzophenon-oxim(51217-59-5)
• EPA Substance Registry System: 5-Chlor-2-amino-4'-methoxy-benzophenon-oxim(51217-59-5)

Safety Data

• Hazardous Substances Data: 51217-59-5(Hazardous Substances Data)

Upstream product

• 728-22-3 3-(4-methoxybenzene)-5-chloro-2,1-benzoisoxazole 

Relevant articles and documents

Practical synthesis of 3-aryl anthranils via an electrophilic aromatic substitution strategy

We report a practical route for the synthesis of valuable 3-aryl anthranils from readily available anthranils and simple arenes by using the classical electrophilic aromatic substitution (EAS) strategy. This transformation goes through an electrophilic substitution and rearomatisation sequence by employing Tf2O as an effective activator. A wide range of arenes were compatible in this transformation, delivering various structurally diversified 3-aryl anthranils in good yields and high regioselectivity. In addition, a variety of readily available feedstocks such as olefins, alkenyl triflates, silyl enolethers, carbonyl compounds, thiophenols and thiols could also participate in the reaction to achieve the C3 alkenylation, alkylation and thioetherification of anthranils. Of note, the synthesized 3-aryl anthranils proved to be a highly robust platform to access a series of biologically active compounds, drug derivatives and organic optoelectronic materials.