51229-65-3

Basic information

• Product Name: Benzene, 1-(bromofluoromethyl)-4-nitro-
• CAS NO: 51229-65-3
• Molecular Formula: C7H5BrFNO2
• Molecular Weight: 234.025
• Mol File: 51229-65-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzene, 1-(bromofluoromethyl)-4-nitro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-(bromofluoromethyl)-4-nitro-(51229-65-3)
• EPA Substance Registry System: Benzene, 1-(bromofluoromethyl)-4-nitro-(51229-65-3)

Safety Data

• Hazardous Substances Data: 51229-65-3(Hazardous Substances Data)

Upstream product

• 500-11-8 4-nitrobenzyl fluoride 
• 100-11-8 1-bromomethyl-4-nitro-benzene 
• 99-99-0 1-methyl-4-nitrobenzene 

Downstream Products

• 51229-67-5 (α-Fluor-4-nitro-benzyl)-phenyl-sulfon 
• 555-16-8 4-nitrobenzaldehdye 

Relevant articles and documents

Visible-Light-Driven Oxidative Mono- and Dibromination of Benzylic sp 3 C-H Bonds with Potassium Bromide/Oxone at Room Temperature

Benzylic sp 3 C-H bonds have been successfully brominated with potassium bromide by using Oxone as an oxidant in water/dichloromethane under visible light at room temperature. Toluene, ethylbenzene and other alkylbenzenes bearing an electron-withdrawing group, such as Br, Cl, COMe, CO 2 Et, CO 2 H, CN or NO 2, provide the corresponding benzylic monobromides in good to excellent yields in this reaction. Dibromides can also be produced in the presence of excess potassium bromide in a prolonged reaction time. Control of the illuminance of visible light (~500 lux) is crucial to achieving both high yield and high selectivity in these brominations. Mono- and difluorides can be conveniently prepared through nucleophilic substitutions of the benzylic bromides with potassium fluoride.