5129-14-6 Usage
Originator
SCF 16046,Smith Kline
Manufacturing Process
A solution of Grignard reactive (prepared from 247 g of o-bromoanisole and
31.6 g of magnesium in 1500 ml of ether) is added dropwise to a solution of
91 g of diphenyl pyruvic acid in ether. The mixture is refluxed for 2 hours.
After cooling to the reaction mixture is added 5% hydrochloric acid and the
product is extracted with 5% solution of sodium hydroxide. α-(o-Anisyl)-β,β-
diphenyl lactic acid is precipitated by addition of concentrated hydrochloric
acid; yield 62 g, melting point 194-195°C.
4 g of α-(o-anisyl)-β,β-diphenyl lactic acid is heated at 210-215°C for 10-15
min. The α-(o-anisyl)-β,β-diphenyl acrylic acid is recrystallized from benzene,
yield 2.85 g (74%), melting point 195-196°C.
Therapeutic Function
Anorexic, Antihyperlipidemic
Check Digit Verification of cas no
The CAS Registry Mumber 5129-14-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,1,2 and 9 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 5129-14:
(6*5)+(5*1)+(4*2)+(3*9)+(2*1)+(1*4)=76
76 % 10 = 6
So 5129-14-6 is a valid CAS Registry Number.
InChI:InChI=1/C22H18O3/c1-25-19-15-9-8-14-18(19)21(22(23)24)20(16-10-4-2-5-11-16)17-12-6-3-7-13-17/h2-15H,1H3,(H,23,24)