51395-42-7 Usage
Originator
Butedronic acid,Bayer A.G.
Manufacturing Process
0.5 mole of methylene diphosphonic acid tetraethyl ester is heated for 6 h to
110°C with 0.5 mole of maleic acid diethyl ester in the presence of 25 ml of a
saturated sodium ethylate solution. The sodium ethylate is then neutralized
with acetic acid and the reaction mixture is quickly distilled invacuo in order to
avoid decomposition. The crude distillate is redistillated, the main fraction
accumulating in the range from 190-213°C at a pressure of 0.05 Torr, yield
50%.
The ester is hydrolyzed by boiling with concentrated hydrochloric acid. 1,1-
Diphosphonopropane-2,3-dicarboxylic acid crystallizes out after purification
with active carbon and concentration of the hydrolysis product, yield 100%.
Therapeutic Function
Diagnostic aid
Check Digit Verification of cas no
The CAS Registry Mumber 51395-42-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,1,3,9 and 5 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 51395-42:
(7*5)+(6*1)+(5*3)+(4*9)+(3*5)+(2*4)+(1*2)=117
117 % 10 = 7
So 51395-42-7 is a valid CAS Registry Number.
InChI:InChI=1/C5H10O10P2/c6-3(7)1-2(4(8)9)5(16(10,11)12)17(13,14)15/h2,5H,1H2,(H,6,7)(H,8,9)(H2,10,11,12)(H2,13,14,15)
