514222-44-7 Usage
Description
FLUCONAZOLE IMPURITY C, also known as 1,1''-(1,3-Phenylene)bis-1H-1,2,4-triazole, is an impurity found in the synthesis of Fluconazole (F421000), a widely used antifungal medication. It is a chemical compound that arises during the production process of Fluconazole and is essential to monitor and control its presence to ensure the safety and efficacy of the final product.
Uses
Used in Pharmaceutical Industry:
FLUCONAZOLE IMPURITY C is used as a reference material for quality control and assurance in the production of Fluconazole (F421000). It is essential to identify, quantify, and control the presence of this impurity to ensure the safety, efficacy, and regulatory compliance of the final drug product.
FLUCONAZOLE IMPURITY C is used as a research compound for the development of analytical methods and techniques to detect and quantify impurities in pharmaceutical products. This helps in the improvement of the overall quality and safety of the drugs, as well as in the development of new and more efficient methods for impurity analysis.
FLUCONAZOLE IMPURITY C is also used as a starting material or intermediate in the synthesis of other related compounds with potential pharmaceutical applications. This can lead to the discovery of new drugs with improved properties or novel therapeutic uses.
Check Digit Verification of cas no
The CAS Registry Mumber 514222-44-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,1,4,2,2 and 2 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 514222-44:
(8*5)+(7*1)+(6*4)+(5*2)+(4*2)+(3*2)+(2*4)+(1*4)=107
107 % 10 = 7
So 514222-44-7 is a valid CAS Registry Number.
514222-44-7Relevant articles and documents
Transition metal coordination complexes based on V-shaped bis-triazole ligand: syntheses, structures, and properties
Shi, Xiu Juan,Chen, Peng Yun,Wu, Ming Ze,Cai, Dong Chen,Tian, Li
, p. 1063 - 1072 (2018)
Hydrothermal reactions of 1,3-bis(1,2,4-triazol-1-yl)benzene (btb) and M(NO3)2 (M?=?Co2+ (1), Cu2+ (2)) afforded two new coordination polymers, [Co(btb)2(NO3)(H2O)]n·NO3·H2O (1) and [Cu(btb)2(NO3)2]n (2), respectively. Single-crystal X-ray diffraction reveals that 1 crystallizes in the space group P21/m and 2 crystallizes in the space group Pī, both showing a double-stranded chain structure. The 1-D chains are interconnected via π?π interactions to lead to 2-D ladder-like supramolecular architectures. In addition, magnetic behavior and thermal stability of 1 and 2 have been investigated. For 1, weak antiferromagnetic interactions are observed at low temperature, and the data obey the Curie–Weiss law χM?=?C/(T?θ), with C?=?3.22?cm3·mol?1·K and θ?=??10.39?K. For 2, the decrease of the χT vs. T curve at low temperature is the result of intermolecular antiferromagnetic magnetic interactions.
Toward molecular rotors: Tetra-N-heterocyclic carbene Ag(i)-halide cubane-type clusters
Clark, Wesley D.,Tyson, Ginger E.,Keith Hollis,Valle, Henry U.,Valente, Edward J.,Oliver, Allen G.,Dukes, Matthew P.
, p. 7338 - 7344 (2013)
1,3-Bis(3′-butylimidazol-1′-yl)benzene diiodide (2a), 1,3-bis(3′-but-3′′-enyl-imidazolium-3′-yl)benzene diiodide (2b), 1,3-bis(3′-pent-4′′-enyl-imidazolium-3′- yl)benzene diiodide (2c), 1,3-bis(4′-butyl-1′,2′,4′- triazolium-1′-yl)benzene diiodide (2d), or