51439-57-7

Basic information

• Product Name: 2-Propenoic acid, 2-(acetylamino)-3-phenyl-, ethyl ester
• CAS NO: 51439-57-7
• Molecular Formula: C13H15NO3
• Molecular Weight: 233.267
• Mol File: 51439-57-7.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 2-Propenoic acid, 2-(acetylamino)-3-phenyl-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propenoic acid, 2-(acetylamino)-3-phenyl-, ethyl ester(51439-57-7)
• EPA Substance Registry System: 2-Propenoic acid, 2-(acetylamino)-3-phenyl-, ethyl ester(51439-57-7)

Safety Data

• Hazardous Substances Data: 51439-57-7(Hazardous Substances Data)

Upstream product

• 881-90-3 4-benzylidene-2-methyl-2-oxazolin-5-one 
• 141-52-6 sodium ethanolate 
• 1227060-32-3 ethyl N-acyl-2-(dimethoxyphosphoryl)glycinate 
• 100-52-7 benzaldehyde 
• 120413-57-2 C₂₉H₂₆NO₂P 
• 620-79-1 Ethyl 2-benzylacetoacetate 
• 100-39-0 benzyl bromide 
• 39149-75-2 ethyl 2-benzyl-2-bromo-3-oxobutanoate 
• 1068-90-2 2-acetylaminomalonic acid diethyl ester 
• 94-41-7 benzalacetophenone 
• 21209-62-1 ethyl hydroxyphenylalaninate 
• 70771-90-3 2-Benzyloxyamino-3-phenyl-propionic acid ethyl ester 
• 120131-62-6 ethyl-2-carbethoxy-2-acetylamino-3,5-diphenyl-5-oxopentanoate 
• 73198-54-6 2-(Acetyl-benzyloxy-amino)-3-phenyl-propionic acid ethyl ester 

Downstream Products

• 2361-96-8 ethyl N-acetyl-(L)-phenylalaninate 
• 2361-96-8 (R)-ethyl N-acetylphenylalanine 

Relevant articles and documents

BABIPhos Family of Biaryl Dihydrobenzooxaphosphole Ligands for Asymmetric Hydrogenation

Novel bidentate phosphine ligands BABIPhos featuring a biaryl bis-dihydrobenzooxaphosphole core are presented. Their synthesis was achieved via Pd-catalyzed reductive homocoupling of dihydrobenzooxaphosphole aryl triflates. An efficient route toward various analogues was also established, giving access to phosphines with different electronic and steric properties. The newly obtained ligands demonstrated high efficiency and selectivity in Rh-catalyzed asymmetric hydrogenation of di- and trisubstituted enamides. This new class of ligands is complementary to previously described bidentate benzooxaphosphole ligands BIBOP.

Reactivity and Selectivity of N-Vinylic λ5-Phosphazenes towards Electrophiles. Synthesis of 2-Aza-1,3-dienes

The reactivity of the P=N double bond of the N-vinylic λ5-phosphazene (1) towards several electrophiles is reported.Intermolecular aza-Wittig reaction of λ5-phosphazene (1) with aldehydes, phenyl isocyanate, and acid anhydrides leads to ethoxycarbonyl 2-aza-1,3-dienes (3), conjugated carbodi-imides (4), and N-protected amino acrylic acid derivatives (5), respectively, while the 2-azahexa-1,3,5-triene (8) and also the pyridine (7) are obtained when dienyl λ5-phosphazenes (6) are used.Reaction of λ5-phosphazene (1) with methyl iodide and acetyl chloride leads to N-alkylated (10) and N-acylated derivatives (11), respectively.Treatment of compound (11) in the presence of amino derivatives affords 1-amino-2-azabuta-1,3-dienes (14).

Eine einfache, allgemein anwendbare Synthese von N-Acetyl-dehydro-α-aminosaeuren

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