514842-83-2

Basic information

• Product Name: 2-Pyrimidinamine, 4-chloro-N-(4-chlorophenyl)-5-(trifluoromethyl)-
• CAS NO: 514842-83-2
• Molecular Formula: C11H6Cl2F3N3
• Molecular Weight: 308.09
• Mol File: 514842-83-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-Pyrimidinamine, 4-chloro-N-(4-chlorophenyl)-5-(trifluoromethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pyrimidinamine, 4-chloro-N-(4-chlorophenyl)-5-(trifluoromethyl)-(514842-83-2)
• EPA Substance Registry System: 2-Pyrimidinamine, 4-chloro-N-(4-chlorophenyl)-5-(trifluoromethyl)-(514842-83-2)

Safety Data

• Hazardous Substances Data: 514842-83-2(Hazardous Substances Data)

Upstream product

• 106-47-8 4-chloro-aniline 
• 3932-97-6 2,4-dichloro-5-trifluoromethylpyrimidine 

Relevant articles and documents

Selective addition of amines to 5-trifluoromethyl-2,4-dichloropyrimidine induced by Lewis acids

A variety of 2,4-diamino-pyrimidine systems can be prepared from the corresponding 2,4-dichloro-pyrimidine by sequential addition of two amines, the first adding selectively to the 4-position. In contrast it was found that 2,4-dichloro-5-trifluoromethyl-p

Pyrimidine derivatives

The present invention relates to trisubstituted pyrimidines of formula (I) 1wherein 0Ra to Re are defined as in claim 1, which are suitable for the treatment of illnesses characterised by excessive or abnormal cell proliferation, the use thereof for preparing a pharmaceutical composition with the abovementioned properties, and processes for the preparation thereof.