514854-15-0

Basic information

• Product Name: 2-Pyrimidinamine,4-ethyl-6-methoxy-(9CI)
• Synonyms: 2-Pyrimidinamine,4-ethyl-6-methoxy-(9CI)
• CAS NO: 514854-15-0
• Molecular Formula: C₇H₁₁N₃O
• Molecular Weight: 153.18174
• Product Categories: METHOXY
• Mol File: 514854-15-0.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 329.7±34.0 °C(Predicted)
• Appearance: /
• Density: 1.134±0.06 g/cm3(Predicted)
• PKA: 6.37±0.10(Predicted)
• CAS DataBase Reference: 2-Pyrimidinamine,4-ethyl-6-methoxy-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pyrimidinamine,4-ethyl-6-methoxy-(9CI)(514854-15-0)
• EPA Substance Registry System: 2-Pyrimidinamine,4-ethyl-6-methoxy-(9CI)(514854-15-0)

Safety Data

• Hazardous Substances Data: 514854-15-0(Hazardous Substances Data)

Upstream product

• 5734-67-8 2-amino-4-chloro-6-ethylpyrimidine 
• 124-41-4 sodium methylate 
• 5734-66-7 6-ethylisocytosine 

Relevant articles and documents

Structural studies on bioactive compounds. Part 37. Suzuki coupling of diaminopyrimidines: A new synthesis of the antimalarial drug pyrimethamine

Suzuki reactions have been used successfully to effect cross-coupling of 5-halopyrimidines with 4-chlorobenzeneboronic acid and 2,4-diamino-5-(4-chloro-3-halo)-6-ethylpyrimidines with 4-methoxybenzeneboronic acid. The antimalarial drug pyrimethamine has been prepared by coupling 2,4-diamino-6-ethyl-5-iodopyrimidine with 4-chlorobenzeneboronic acid.