51486-04-5

Basic information

• Product Name: 2-AMINO-4,5-DIMETHYLTHIOPHENE-3-CARBOXAMIDE
• Synonyms: TIMTEC-BB SBB000163;ART-CHEM-BB B000687;2-AMINO-4,5-DIMETHYL-3-THIOPHENECARBOXAMIDE;2-AMINO-4,5-DIMETHYLTHIOPHENE-3-CARBOXAMIDE;2-AMINO-4,5-DIMETHYL-THIOPHENE-3-CARBOXYLIC ACID AMIDE;AKOS MSC-0461;AKOS BB/0054;AKOS B000687
• CAS NO: 51486-04-5
• Molecular Formula: C₇H₁₀N₂OS
• Molecular Weight: 170.23
• Mol File: 51486-04-5.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 252.1 °C at 760 mmHg
• Flash Point: 106.3 °C
• Appearance: /
• Density: 1.285 g/cm³
• Vapor Pressure: 0.0197mmHg at 25°C
• Refractive Index: 1.635
• CAS DataBase Reference: 2-AMINO-4,5-DIMETHYLTHIOPHENE-3-CARBOXAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-4,5-DIMETHYLTHIOPHENE-3-CARBOXAMIDE(51486-04-5)
• EPA Substance Registry System: 2-AMINO-4,5-DIMETHYLTHIOPHENE-3-CARBOXAMIDE(51486-04-5)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 22
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 51486-04-5(Hazardous Substances Data)

Usage

General Description

2-amino-4,5-dimethylthiophene-3-carboxamide is a chemical compound with the molecular formula C8H11N3OS. It is a derivative of the thiophene ring, containing an amide functional group and a tertiary amine group. 2-AMINO-4,5-DIMETHYLTHIOPHENE-3-CARBOXAMIDE is used in organic synthesis and pharmaceutical research as a building block for the synthesis of various biologically active molecules. It is also known for its potential antibacterial and antifungal properties, making it an important catalyst in the development of new drugs and pharmaceuticals. Additionally, 2-amino-4,5-dimethylthiophene-3-carboxamide has shown potential as an ingredient in the production of agrochemicals and materials science applications.

InChI:InChI=1/C7H10N2OS/c1-3-4(2)11-7(9)5(3)6(8)10/h9H2,1-2H3,(H2,8,10)

Upstream product

• 4651-94-9 2-amino-4,5-dimethylthiophene-3-carbonitrile 
• 78-93-3 butanone 
• 107-91-5 cyanoacetic acid amide 

Downstream Products

• 60442-57-1 2-(4-methoxy-phenyl)-5,6-dimethyl-3H-thieno[2,3-d]pyrimidin-4-one 
• 109164-38-7 N-(3-Carbamoyl-4,5-dimethyl-thiophen-2-yl)-succinamic acid 
• 314284-15-6 2-(2-chlorobenzamido)-4,5-dimethylthiophene-3-carboxamide 
• 314284-10-1 2-benzamido-4,5-dimethylthiophene-3-carboxamide 
• 349637-87-2 2-(4-chlorobenzamido)-4,5-dimethylthiophene-3-carboxamide 
• 541543-03-7 2-(4-bromobenzamido)-4,5-dimethylthiophene-3-carboxamide 
• 20681-31-6 5,6-dimethyl-2-(4-methylphenyl)thieno[2,3-d]pyrimidin-4(3H)-one 
• 357620-23-6 2-(4-chlorophenyl)-5,6-dimethylthieno[2,3-d]pyrimidin-4(3H)-one 
• 357621-16-0 5,6-dimethyl-2-(3-nitrophenyl)-3,4-dihydrothieno[2,3-d]pyrimidin-4(3H)-one 
• 18593-46-9 5,6-dimethyl-2-phenylthieno<2,3-d>pyrimidin-4(3H)-one 
• 357620-25-8 2-(2-hydroxyphenyl)-5,6-dimethyl-3,4-dihydrothieno[2,3-d]pyrimidin-4(3H)-one 
• 357620-19-0 2-(4-bromophenyl)-5,6-dimethylthieno[2,3-d]pyrimidin-4(3H)-one 
• 1182020-85-4 5,6-dimethyl-2-(4-methylphenyl)-2,3-dihydrothieno[2,3-d]pyrimidin-4(1H)-one 
• 335215-30-0 2-(4-chlorophenyl)-5,6-dimethyl-2,3-dihydrothieno[2,3-d]pyrimidin-4(1H)-one 

Relevant articles and documents

Synthesis and characterization of 1,2,4-triazolo[1,5-a]pyrimidine-2-carboxamide-based compounds targeting the PA-PB1 interface of influenza A virus polymerase

Influenza viruses (Flu) are responsible for seasonal epidemics causing high rates of morbidity, which can dramatically increase during severe pandemic outbreaks. Antiviral drugs are an indispensable weapon to treat infected people and reduce the impact on

A novel series of positive modulators of the AMPA receptor: Discovery and structure based hit-to-lead studies

Starting from an HTS derived hit 1, application of biostructural data facilitated rapid optimization to lead 22, a novel AMPA receptor modulator. This is the first demonstration of how structure based drug design can be exploited in an optimization program for a glutamate receptor.

PYRAZOLEALKANAMIDE SUBSTITUTED THIOPHENES AS AMPA POTENTIATORS

The present invention relates to a heterocyclic derivative according to Formula (I) wherein the variables are defined as in the specification, or to a pharmaceutically acceptable salt or solvate thereof. The present invention also relates to a pharmaceuti