51503-08-3 Usage
Description
(4-TERT-BUTOXY-PHENYL)-METHANOL, also known as 4-tert-butoxybenzyl alcohol, is an organic compound with the chemical formula C11H16O2. It is a colorless to pale yellow liquid with a mild characteristic odor. (4-TERT-BUTOXY-PHENYL)-METHANOL is characterized by its hydroxyl and tert-butoxy groups, which contribute to its reactivity and potential applications in various industries.
Uses
Used in Pharmaceutical Industry:
(4-TERT-BUTOXY-PHENYL)-METHANOL is used as a reactant for the preparation of pyrimidinediones and triazinediones. These compounds serve as prokineticin 1 receptor antagonists, which have potential applications in the treatment of various gastrointestinal disorders and conditions related to gastrointestinal motility.
Used in Chemical Synthesis:
(4-TERT-BUTOXY-PHENYL)-METHANOL can be utilized as an intermediate in the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and other specialty chemicals. Its unique structural features make it a valuable building block for the development of new molecules with specific biological activities.
Used in Research and Development:
As a versatile organic compound, (4-TERT-BUTOXY-PHENYL)-METHANOL is also employed in research and development laboratories for the exploration of new chemical reactions, synthesis methods, and the development of novel compounds with potential applications in various fields.
Check Digit Verification of cas no
The CAS Registry Mumber 51503-08-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,1,5,0 and 3 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 51503-08:
(7*5)+(6*1)+(5*5)+(4*0)+(3*3)+(2*0)+(1*8)=83
83 % 10 = 3
So 51503-08-3 is a valid CAS Registry Number.
InChI:InChI=1/C11H16O2/c1-11(2,3)13-10-6-4-9(8-12)5-7-10/h4-7,12H,8H2,1-3H3
51503-08-3Relevant articles and documents
Structure of a complex formed by a protein and a helical aromatic oligoamide foldamer at 2.1 ? resolution
Buratto, Jérémie,Colombo, Cinzia,Stupfel, Marine,Dawson, Simon J.,Dolain, Christel,Langlois D'Estaintot, Béatrice,Fischer, Lucile,Granier, Thierry,Laguerre, Michel,Gallois, Bernard,Huc, Ivan
supporting information, p. 883 - 887 (2014/01/23)
In the search of molecules that could recognize sizeable areas of protein surfaces, a series of ten helical aromatic oligoamide foldamers was synthesized on solid phase. The foldamers comprise three to five monomers carrying various proteinogenic side chains, and exist as racemic mixtures of interconverting right-handed and left-handed helices. Functionalization of the foldamers by a nanomolar ligand of human carbonic anhydrase II (HCA) ensured that they would be held in close proximity to the protein surface. Foldamer-protein interactions were screened by circular dichroism (CD). One foldamer displayed intense CD bands indicating that a preferred helix handedness is induced upon interacting with the protein surface. The crystal structure of the complex between this foldamer and HCA could be resolved at 2.1 ? resolution and revealed a number of unanticipated protein-foldamer, foldamer-foldamer, and protein-protein interactions. To design a foldamer that binds to a protein surface, a strategy is proposed that uses a known protein ligand to tether the foldamer to the protein surface. Candidates are first screened for induced circular dichroism in presence of the protein. Then, structural information about foldamer-protein interactions is collected before strong binding is established. The crystal structure of human carbonic anhydrase (A, B chains) with helical aromatic amide foldamers (stick models) is shown. Copyright
