515160-73-3 Usage
Description
1-(2-fluoro-4-(2-methoxyethoxy)phenyl)piperazine, also known as 2-F-4-MPEP, is a chemical compound belonging to the class of piperazine derivatives. It features a piperazine ring and a fluoro substituted phenyl ring with a methoxyethoxy group attached to it. 1-(2-fluoro-4-(2-methoxyethoxy)phenyl)piperazine has been investigated for its potential applications in medicinal chemistry, particularly in the development of pharmaceutical drugs. It has shown affinity for certain receptors in the central nervous system and may hold promise as a therapeutic agent for specific neurological disorders. However, further research is required to fully comprehend its pharmacological properties and potential uses.
Uses
Used in Pharmaceutical Development:
1-(2-fluoro-4-(2-methoxyethoxy)phenyl)piperazine is used as a compound in pharmaceutical development for its potential interaction with central nervous system receptors. Its application is aimed at developing therapeutic agents for neurological disorders due to its demonstrated affinity for these receptors.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, 1-(2-fluoro-4-(2-methoxyethoxy)phenyl)piperazine is used as a subject of study to explore its pharmacological properties. The research is focused on understanding its potential as a therapeutic agent for neurological disorders and identifying its full range of applications in drug development.
Check Digit Verification of cas no
The CAS Registry Mumber 515160-73-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,1,5,1,6 and 0 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 515160-73:
(8*5)+(7*1)+(6*5)+(5*1)+(4*6)+(3*0)+(2*7)+(1*3)=123
123 % 10 = 3
So 515160-73-3 is a valid CAS Registry Number.
515160-73-3Relevant articles and documents
3H-[1,2,4]-Triazolo[5,1-i]purin-5-amine derivatives as adenosine A2A antagonists
Silverman, Lisa S.,Caldwell, John P.,Greenlee, William J.,Kiselgof, Eugenia,Matasi, Julius J.,Tulshian, Deen B.,Arik, Leyla,Foster, Carolyn,Bertorelli, Rosalia,Monopoli, Angela,Ongini, Ennio
, p. 1659 - 1662 (2007/10/03)
A novel series of 3-substituted-8-aryl-[1,2,4]-triazolo[5,1-i]purin-5-amine analogs related to Sch 58261 was synthesized in order to identify potent adenosine A2A receptor antagonists with improved selectivity over the A1 receptor, physiochemical properties, and pharmacokinetic profiles as compared to those of Sch 58261. As a result of structural modifications, numerous analogs with excellent in vitro binding affinities and selectivities were identified. Moreover, compound 27 displayed both superior in vitro and highly promising in vivo profiles.
2-Heteroaryl-pyrazolo-[4,3-e]-1,2,4-triazolo-[1,5-c]-pyrimidine adenosine A2a receptor antagonists
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Page/Page column 10, (2008/06/13)
Compounds having the structural formula I or a pharmaceutically acceptable salt thereof, wherein R is R1-isoxazolyl, R1-oxadiazolyl, R1-dihydrofuranyl, R1-pyrazolyl, R1-imidazolyl, R1-pyrazinyl or R1-pyrimidinyl; R1 is 1, 2 or 3 substituents selected from H, alkyl, alkoxy and halo; Z is optionally substituted-aryl, or optionally substituted-heteroaryl; are disclosed, as well as their use in the treatment of central nervous system diseases, in particular Parkinson's disease and Extra Pyramidal Syndrome, pharmaceutical compositions comprising them, and combinations with other agents.
