51529-97-6Relevant articles and documents
BCL-2 INHIBITOR
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Paragraph 0506-0508, (2021/10/22)
Disclosed herein is a compound of Formula (I) for inhibiting both Bcl-2 wild type and mutated Bcl-2, in particular, Bcl-2 G101V and D103Y, and a method of using the compound disclosed herein for treating dysregulated apoptotic diseases.
BI-CYCLO ALDEHYDE AS PERFUMING INGREDIENT
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Page/Page column 11-12, (2015/01/16)
The present invention relates to the field of perfumery and concerns some bi-cyclo derivative of formula (I), wherein R1 represents a hydrogen atom or a C1-2 alkyl group; R2 represents a hydrogen atom or a methyl group; and A represents a group of formula C3-5 alkanediyl group; at least one of said R1 or R2 represents a group containing at least one carbon atom; and said compound being in the form of a E or Z isomer or of a mixture thereof. Said compounds are valuable perfuming ingredients capable of imparting lily of the valley and citrus notes.
Synthesis of aromatic aldehydes by organocatalytic [4+2] and [3+3] cycloaddition of α,β-unsaturated aldehydes
Hong, Bor-Cherng,Tseng, Hsing-Chang,Chen, Shang-Hung
, p. 2840 - 2850 (2007/10/03)
Organocatalytic inter- and intramolecular [4+2] and [3+3] cycloadditions of α,β-unsaturated aldehydes to give polysubstituted aromatic aldehydes are described. High periselectivity for the cycloadditions, with catalyst effects exerted by l-proline and pyrrolidine-HOAc, as well as cocatalyst, additive effects, has been observed.