5160-60-1Relevant articles and documents
A Computerised Least Square Method for Determination of Stability Constants of 1:1 Molecular Complexes and Chemical Shift of Pure Complexes from Nuclear Magnetic Resonance Data
Seal, B. K.,Mukherjee, A. K.
, p. 413 - 415 (2007/10/02)
A computerised method utilising nuclear magnetic resonance data has been developed for the determination of stability constants of 1:1 molecular complexes.It is based on the principle of least squares in which the coefficients are adjusted under a constraint with the help of Lagrange's method of undetermined multipliers.The method utilises the complete expression for equilibrium constant and is mathematically rigorous, straightforward, non-iterative and requires very little computer time.
