51607-16-0

Basic information

• Product Name: 2,3-O-ISOPROPYLIDENE-D-ERYTHRONOLACTONE
• Synonyms: 2,3-O-ISOPROPYLIDENE-D-ERYTHRONOLACTOL;(-)-2,3-O-ISOPROPYLIDENE-D-ERYTHRONO-LACTONE;2,3-O-ISOPROPYLIDENE-D-ERYTHRONOLACTONE
• CAS NO: 51607-16-0
• Molecular Formula: C₇H₁₂O₄
• Molecular Weight: 158.15
• Mol File: 51607-16-0.mol
• Article Data: 8

Chemical Properties

• Melting Point: 67-69 °C(lit.)
• Boiling Point: 249.1±25.0 °C(Predicted)
• Appearance: /
• Density: 1.192±0.06 g/cm3(Predicted)
• PKA: 14.20±0.10(Predicted)
• CAS DataBase Reference: 2,3-O-ISOPROPYLIDENE-D-ERYTHRONOLACTONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-O-ISOPROPYLIDENE-D-ERYTHRONOLACTONE(51607-16-0)
• EPA Substance Registry System: 2,3-O-ISOPROPYLIDENE-D-ERYTHRONOLACTONE(51607-16-0)

Safety Data

• Safety Statements: 22-24/25
• WGK Germany: 3
• Hazardous Substances Data: 51607-16-0(Hazardous Substances Data)

Usage

Physical State

White crystalline solid

Derivative

Isopropylidene derivative of D-erythronolactone

Usage

Starting material in synthesis of various compounds, including pharmaceuticals and agrochemicals

Role in Organic Synthesis

Acts as a protective group for the hydroxyl group in carbohydrates and related compounds

Biological Activity

Studied for potential inhibitory effects on enzymes
Investigated for potential therapeutic applications

Versatility

Serves as a key component in organic chemistry and pharmaceutical research

Upstream product

• 67-56-1 methanol 
• 93496-36-7 2,3-O-isopropylidene-β-D-erythrofuranosyl (Z)-3-acetyl-3-hydroxymethylacrylate 
• 93496-22-1 ethyl 2,3-O-isopropylidene-β-D-erythrofuranosyl 3-acetylfumarate 
• 64-17-5 ethanol 
• 93496-25-4 ethyl 2,3-O-isopropylidene-β-D-erythrofuranosyl 2-acetyl-3-methoxysuccinate 
• 583-50-6 D-erythrose 
• 67-64-1 acetone 
• 25581-41-3 D-erythronolactone acetonide 
• 24877-23-4 ethyl 5-(2',3'-O-isopropylidene-β-D-erythrofuranosyl)-2-methylfuran-3-carboxylate 
• 93496-23-2 1-((3aR,4R,6aR)-2,2-Dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl)-4-methyl-2,3,7-trioxa-bicyclo[2.2.1]hept-5-ene-5-carboxylic acid ethyl ester 
• 93253-48-6 3-hydroxymethyl-5-(2,3-O-isopropylidene-β-D-erythro-furanosyl)-2-methylfuran 
• 21335-55-7 n-pentenyl alcohol 

Downstream Products

• 127758-25-2 (4R,5S)-(2,2-dimethyl-5-vinyl-1,3-dioxolan-4-yl)methan-1-ol 
• 205866-39-3 (Z)-(S)-5-Benzyloxy-1-((4S,5R)-5-hydroxymethyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-pent-2-en-1-ol 
• 205866-16-6 (E)-(S)-5-Benzyloxy-1-((4S,5R)-5-hydroxymethyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-pent-2-en-1-ol 
• 205866-19-9 (E)-(R)-3-(2-Benzyloxy-ethyl)-5-((4S,5R)-5-hydroxymethyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-pent-4-enoic acid methyl ester 
• 205866-42-8 (E)-(S)-3-(2-Benzyloxy-ethyl)-5-((4S,5R)-5-hydroxymethyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-pent-4-enoic acid methyl ester 
• 205866-47-3 (3aR,8R,9S,9aS,9bS)-8-(2-Benzyloxy-ethyl)-2,2-dimethyl-octahydro-[1,3]dioxolo[4,5-a]indolizin-9-ol 
• 205866-24-6 (3aR,8S,9R,9aR,9bS)-8-(2-Benzyloxy-ethyl)-2,2-dimethyl-octahydro-[1,3]dioxolo[4,5-a]indolizin-9-ol 
• 205866-46-2 (3aR,8R,9R,9aR,9bS)-8-(2-Benzyloxy-ethyl)-2,2-dimethyl-octahydro-[1,3]dioxolo[4,5-a]indolizin-9-ol 
• 205866-21-3 (R)-3-[3-((4R,5R)-5-Azidomethyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-oxiranyl]-5-benzyloxy-pentanoic acid methyl ester 
• 205866-44-0 (S)-3-[3-((4R,5R)-5-Azidomethyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-oxiranyl]-5-benzyloxy-pentanoic acid methyl ester 
• 205866-20-2 (E)-(R)-5-((4S,5R)-5-Azidomethyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-3-(2-benzyloxy-ethyl)-pent-4-enoic acid methyl ester 
• 205866-43-9 (E)-(S)-5-((4S,5R)-5-Azidomethyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-3-(2-benzyloxy-ethyl)-pent-4-enoic acid methyl ester 
• 205866-22-4 (3aR,8R,9S,9aS,9bS)-8-(2-Benzyloxy-ethyl)-9-hydroxy-2,2-dimethyl-hexahydro-[1,3]dioxolo[4,5-a]indolizin-6-one 
• 205866-23-5 (3aR,8R,9R,9aR,9bS)-8-(2-Benzyloxy-ethyl)-9-hydroxy-2,2-dimethyl-hexahydro-[1,3]dioxolo[4,5-a]indolizin-6-one 

Relevant articles and documents

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Synthesis and mannosidase inhibitory activity of 6- and 7-substituted analogs of swainsonine

Swainsonine (1), an inhibitor of the important glycoprotein-processing enzyme Golgi α-mannosidase II, is a clinical candidate for cancer treatment. Analogs bearing substituents at C-6 and C-7 have been prepared and evaluated as inhibitors of α-mannosidase

Complete Reverse Regioselection in Wacker Oxidation of Acetonides and Cyclic Carbonates of Allylic Diols

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