5164-37-4

Basic information

• Product Name: 1-methyl-4,4a,5,6,7,8-hexahydronaphthalen-2(3H)-one
• CAS NO: 5164-37-4
• Molecular Formula: C₁₁H₁₆O
• Molecular Weight: 164.2441
• Mol File: 5164-37-4.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 274.5°C at 760 mmHg
• Flash Point: 110.5°C
• Density: 1g/cm³
• Vapor Pressure: 0.00538mmHg at 25°C
• Refractive Index: 1.503
• CAS DataBase Reference: 1-methyl-4,4a,5,6,7,8-hexahydronaphthalen-2(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-methyl-4,4a,5,6,7,8-hexahydronaphthalen-2(3H)-one(5164-37-4)
• EPA Substance Registry System: 1-methyl-4,4a,5,6,7,8-hexahydronaphthalen-2(3H)-one(5164-37-4)

Safety Data

• Hazardous Substances Data: 5164-37-4(Hazardous Substances Data)

Usage

General Description

1-methyl-4,4a,5,6,7,8-hexahydronaphthalen-2(3H)-one, also known as dihydrocivettone, is a synthetic compound commonly used in the production of fragrances. It is classified as a ketone and belongs to the family of naphthalenones. This chemical is known for its musky and animalic aroma, making it a popular ingredient in perfumes and colognes. Its odor profile has been described as warm, woody, and slightly sweet, with a hint of leather and tobacco. Dihydrocivettone is often used to add depth and complexity to fragrance compositions, and is commonly found in both men's and women's fragrances.

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Relevant articles and documents

Synthesis of 2-Octalones from Quinaldine

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A new method for the preparation of Michael adducts and cyclic enones using lithium chloride-hexamethylphosphoramide system

A new procedure using lithium chloride in hexamethylphosphoramide was found to be useful for the synthesis of Michael-type adducts and cyclic enones. Selectivity for the two products could be controlled by altering the reaction temperature employed. The urea-type solvents were also examined instead of hexamethylphosphoramide.

A Method for the Cyclic Enone Synthesis Using Lithium Chloride-Hexamethylphosphoramide System

Cyclic enones were obtained from the reactions of β-keto esters with acyclic α,β-unsaturated ketones by using lithium chloride in hexamethylphosphoramide.The products were brought via the Michael addition, decarboxylation, and the aldol condensation.