51642-03-6

Basic information

• Product Name: 3-AMINOTETRAHYDRO-1H-1LAMBDA6-THIOPHENE-1,1-DIONE HYDROCHLORIDE
• Synonyms: Tetrahydro-3-thiophenaMine 1,1-dioxide HCl;3-Aminotetrahydrothiopene 1,1-dioxide hydrochloride;3-AMINOTHIOLANE-1,1-DIONE, HYDROCHLORIDE;3-AMINOTETRAHYDRO-1H-1LAMBDA6-THIOPHENE-1,1-DIONE HYDROCHLORIDE;1,1-DIOXIDOTETRAHYDROTHIEN-3-YLAMINE HYDROCHLORIDE;TETRAHYDRO-3-THIOPHENAMINE 1,1-DIOXIDE HYDROCHLORIDE;TETRAHYDROTHIOPHEN-3-AMINIUM 1,1-DIOXIDE CHLORIDE;1,1-Dioxo-tetrahydrothiphen-3-ylamine, hydrochloride
• CAS NO: 51642-03-6
• Molecular Formula: C₄H₉NO₂S*ClH
• Molecular Weight: 171.65
• Mol File: 51642-03-6.mol
• Article Data: 5

Chemical Properties

• Melting Point: 208 °C
• Boiling Point: 334.9 °C at 760 mmHg
• Flash Point: 156.3 °C
• Appearance: /
• Density: 1.314g/cm³
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 3-AMINOTETRAHYDRO-1H-1LAMBDA6-THIOPHENE-1,1-DIONE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-AMINOTETRAHYDRO-1H-1LAMBDA6-THIOPHENE-1,1-DIONE HYDROCHLORIDE(51642-03-6)
• EPA Substance Registry System: 3-AMINOTETRAHYDRO-1H-1LAMBDA6-THIOPHENE-1,1-DIONE HYDROCHLORIDE(51642-03-6)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 51642-03-6(Hazardous Substances Data)

Usage

Uses

1,1-Dioxidotetrahydrothien-3-ylamine, HCl

Upstream product

• 24373-67-9 methyl 1,1-dioxo-3-thiolanylcarbamate 
• 77-79-2 3-Sulfolene 
• 60-29-7 diethyl ether 

Downstream Products

• 1192712-06-3 2-chloro-N-(1,1-dioxy-tetrahydrothiophen-3-yl)-7-tosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine 
• 1208004-98-1 3-[{1-[bis(4-chlorophenyl)methyl]azetidin-3-yl}(methylsulphonyl)amino]-N-(1,1-dioxidotetrahydrothiophen-3-yl)benzamide 

Relevant articles and documents

INDAZOLE DERIVATIVES USEFUL AS INHIBITORS OF DIACYLGLYCERIDE O-ACYLTRANSFERASE 2

The present invention relates to a compound represented by formula I': and pharmaceutically acceptable salts thereof. The compounds of formula I are inhibitors of diacylglyceride O-acyltransferase 2 ( DGAT2 ) and may be useful in the treatment, prevention and suppression of diseases mediated by DGAT2. The compounds of the present invention may be useful in the treatment of hepatic steatosis, diabetes mellitus, obesity, hyperlipidemia, hypercholesterolemia, atherosclerosis, cardiorenal diseases such as chronic kidney diseases and heart failure and related diseases and conditions.

KINASE INHIBITOR COMPOUNDS

The invention relates to compounds, compositions comprising the compounds, and methods of using the compounds and compound compositions. The compounds, compositions, and methods described herein can be used for the therapeutic modulation of kinase-mediated processes, and treatment of disease and disease symptoms, particularly those mediated by certain kinase enzymes.

Aminoalkylenephosphonic acids and salts thereof and their use in aqueous systems

Aminoalkylenephosphonic acids and their alkali metal salts prepared by a reaction utilizing a primary or secondary tetrahydrothiophenamine 1,1-dioxide or the hydrochloride thereof, an aldehyde or a ketone, and orthophosphorous acid are useful in the control of scale and sludge deposition in aqueous systems. When used in combination with known corrosion inhibitors they show synergistic results in inhibiting corrosion of metal surfaces in contact with an aqueous system that is normally corrosive to such metals.