516473-23-7

Basic information

• Product Name: 1-[(S)-O-5-isoquinolinesulfonyl-N-tert-butyloxycarbonyl-N-methyltyrosyl]-4-(4-fluorobenzoyl)piperazine
• Synonyms: 1-[(S)-O-5-isoquinolinesulfonyl-N-tert-butyloxycarbonyl-N-methyltyrosyl]-4-(4-fluorobenzoyl)piperazine
• CAS NO: 516473-23-7
• Molecular Weight: 676.766
• Mol File: 516473-23-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-[(S)-O-5-isoquinolinesulfonyl-N-tert-butyloxycarbonyl-N-methyltyrosyl]-4-(4-fluorobenzoyl)piperazine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[(S)-O-5-isoquinolinesulfonyl-N-tert-butyloxycarbonyl-N-methyltyrosyl]-4-(4-fluorobenzoyl)piperazine(516473-23-7)
• EPA Substance Registry System: 1-[(S)-O-5-isoquinolinesulfonyl-N-tert-butyloxycarbonyl-N-methyltyrosyl]-4-(4-fluorobenzoyl)piperazine(516473-23-7)

Safety Data

• Hazardous Substances Data: 516473-23-7(Hazardous Substances Data)

Upstream product

• 102391-98-0 1-(4-fluorobenzoyl)piperazine 
• 82038-34-4 (S)-2-((tert-butoxycarbonyl)(methyl)amino)-3-(4-hydroxyphenyl)propanoic acid 
• 84468-15-5 5-isoquinolinesulfonyl chloride 
• 516472-94-9 1-[(S)-N-tert-butyloxycarbonyl-N-methyltyrosyl]-4-(4-fluorobenzoyl)piperazine 

Relevant articles and documents

Synthesis and biological activity of N-arylpiperazine-modified analogues of KN-62, a potent antagonist of the purinergic P2X7 receptor

The P2X7 receptor is involved in several processes relevant to inflammation (cytokine release, NO generation, killing of intracellular pathogens, cytotoxicity); thus, it may be an appealing target for pharmacological intervention. The character