51665-54-4

Basic information

• Product Name: dihydroepiberberine
• Synonyms: dihydroepiberberine
• CAS NO: 51665-54-4
• Molecular Weight: 337.375
• Mol File: 51665-54-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: dihydroepiberberine(CAS DataBase Reference)
• NIST Chemistry Reference: dihydroepiberberine(51665-54-4)
• EPA Substance Registry System: dihydroepiberberine(51665-54-4)

Safety Data

• Hazardous Substances Data: 51665-54-4(Hazardous Substances Data)

Upstream product

• 63375-81-5 2-(2-bromo-4,5-dimethoxyphenylphenyl)ethan-1-amine 

Downstream Products

• 6873-09-2 Epiberberine 

Relevant articles and documents

Convenient synthesis of 2,3,9,10-tetraoxygenated protoberberine alkaloids and their 13-methyl alkaloids

New and convenient synthesis of 2,3,9,10-tetraoxygenated protoberberine alkaloids and their 13-methyl alkaloids through the same intermediates was developed. Acylation of the brominated benzylphenethylamine (13) with α- chloro-α-(methylthio)acetyl chloride, followed by cyclization with stannic chloride, furnished the key intermediates 4-methylthio-3- phenethylisoquinolin-3-ones (14), which were methylated to provide their methyl derivatives (17). Both isoquinolin-3-ones (14, 17) were easily transformed into protoberberine alkaloids (16) and their 13-methyl alkaloids (21) in good yield.