51671-33-1

Basic information

• Product Name: 1H-1,2,3-Triazole, 4-methyl-5-phenyl-1-(phenylmethyl)-
• CAS NO: 51671-33-1
• Molecular Formula: C16H15N3
• Molecular Weight: 249.315
• Mol File: 51671-33-1.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: 1H-1,2,3-Triazole, 4-methyl-5-phenyl-1-(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-1,2,3-Triazole, 4-methyl-5-phenyl-1-(phenylmethyl)-(51671-33-1)
• EPA Substance Registry System: 1H-1,2,3-Triazole, 4-methyl-5-phenyl-1-(phenylmethyl)-(51671-33-1)

Safety Data

• Hazardous Substances Data: 51671-33-1(Hazardous Substances Data)

Upstream product

• 590-93-2 2-Butynoic acid 
• 622-79-7 benzyl azide 
• 98-80-6 phenylboronic acid 
• 79-24-3 Nitroethane 
• 100-52-7 benzaldehyde 
• 705-60-2 (2-nitroprop-1-enyl)benzene 
• 100-39-0 benzyl bromide 
• 536-74-3 phenylacetylene 
• 74-88-4 methyl iodide 
• 673-32-5 1-Phenylprop-1-yne 
• 6926-47-2 diphenylmethylazide 

Relevant articles and documents

Insight into the Mechanism of the CuAAC Reaction by Capturing the Crucial Au4Cu4-π-Alkyne Intermediate

The classic Fokin mechanism of the CuAAC reaction of terminal alkynes using a variety of Cu(I) catalysts is well-known to include alkyne deprotonation involving a bimetallic σ,π-alkynyl intermediate. In this study, we have designed a CNT-supported atomica

Synergistic Effect of Copper and Ruthenium on Regioselectivity in the Alkyne-Azide Click Reaction of Internal Alkynes

Cu(I) salts have been shown to improve the regioselectivity and rate of the Ru-catalyzed alkyne-azide click reaction of internal alkynes with azides. While Cu and Ru individually provide complementary regioselectivity in the case of terminal alkynes, the

A metal-free three-component reaction for the regioselective synthesis of 1,4,5-trisubstituted 1,2,3-triazoles

A metal-free three-component reaction to synthesize 1,4,5-trisubstituted 1,2,3-triazoles from readily available building blocks,such as aldehydes,nitroalkanes,and organic azides,is described. The process is enabled by an organocatalyzed Knoevenagel condensation of the formyl group with the nitro compound,which is followed by the 1,3-dipolar cycloaddition of the azide to the activated alkene. The reaction features an excellent substrate scope,and the products are obtained with high yield and regioselectivity. This method can be utilized for the synthesis of fused triazole heterocycles and materials with several triazole moieties.