51693-17-5 Usage
Description
(S)-(+)-5-(Hydroxymethyl)-2-pyrrolidinone p-toluenesulfonate is a colorless to beige powder that serves as a crucial building block in the synthesis of various organic compounds, including (R)and (S)-diaminovaleric acids and 5-azasemicorrin bidentate nitrogen ligands for enantioselective catalysis. Its unique chemical structure and properties make it a valuable component in the development of new pharmaceuticals and catalysts.
Uses
Used in Pharmaceutical Synthesis:
(S)-(+)-5-(Hydroxymethyl)-2-pyrrolidinone p-toluenesulfonate is used as a building block for the synthesis of (R)and (S)-diaminovaleric acids, which are essential components in the development of various pharmaceuticals. These diamines play a significant role in the creation of drugs targeting specific medical conditions, making this compound a vital part of the pharmaceutical industry.
Used in Enantioselective Catalysis:
In the field of enantioselective catalysis, (S)-(+)-5-(Hydroxymethyl)-2-pyrrolidinone p-toluenesulfonate is used as a key component in the synthesis of 5-azasemicorrin bidentate nitrogen ligands. These ligands are crucial for the development of enantioselective catalysts, which are essential in producing chiral compounds with high selectivity and purity. This application is particularly important in the synthesis of pharmaceuticals, agrochemicals, and fine chemicals, where the enantiomeric purity of the product is critical.
Used in Chemical Research and Development:
(S)-(+)-5-(Hydroxymethyl)-2-pyrrolidinone p-toluenesulfonate is also utilized in chemical research and development, where its unique properties and reactivity are explored for the creation of new compounds and materials. Its versatility as a building block allows researchers to design and synthesize novel molecules with potential applications in various industries, including pharmaceuticals, materials science, and environmental science.
Check Digit Verification of cas no
The CAS Registry Mumber 51693-17-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,1,6,9 and 3 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 51693-17:
(7*5)+(6*1)+(5*6)+(4*9)+(3*3)+(2*1)+(1*7)=125
125 % 10 = 5
So 51693-17-5 is a valid CAS Registry Number.
InChI:InChI=1/C12H15NO4S/c1-9-2-5-11(6-3-9)18(15,16)17-8-10-4-7-12(14)13-10/h2-3,5-6,10H,4,7-8H2,1H3,(H,13,14)/t10-/m0/s1
51693-17-5Relevant articles and documents
Synthesis of N-aminomethylpyrrolidin-2-ones
Chen, Ping,Suh, Dong-Jin,Smith, Michael B.
, p. 1317 - 1322 (1995)
Pyrrolidin-2-ones react with formaldehyde and chlorotrimethylsilane to give 1-chloromethylpyrrolidin-2-ones which upon subsequent reaction with primary and secondary amines give 1-aminomethylpyrrolidin-2-ones in good yield.
NOVEL FUNCTIONALIZED LACTAMS AS MODULATORS OF THE 5-HYDROXYTRYPTAMINE RECEPTOR 7 AND THEIR METHOD OF USE
-
Paragraph 000723-000724, (2021/05/21)
Described herein are new, selective modulators of the 5 -HT7 receptor. These selective compounds can be useful for the treatment of CNS and non-CNS indications. Compounds described herein can be selective in targeting 5-HT7 receptors
Synthesis of optically active (R)- And (S)-β-arginine from pyroglutamic acid
Yasuno, Yoko,Sawai, Akira,Sekihara, Ai,Shinada, Tetsuro
, p. 165 - 176 (2020/02/04)
– The first synthesis of optically active β-arginine was achieved starting from commercially available pyroglutamic acid. The new synthetic protocol is characterized by the use of nitrile as a carboxylic acid surrogate which could be transformed to the co
