51705-58-9 Usage
Description
[3aR,4R(1E,3R),5R,6aS]-5-benzoyloxy-4-(3-hydroxyocten-1-yl)-hexahydro-2H-cyclopenta[b]furan-2-one is a complex organic compound belonging to the cyclopentafuranone derivative class. It features a molecular formula of C22H28O5 and is characterized by the presence of a benzoyloxy group at the 5th carbon and a long hydrocarbon chain at the 4th carbon. [3aR,4R(1E,3R),5R,6aS]-5-benzoyloxy-4-(3-hydroxyocten-1-yl)-hexahydro-2H-cyclopenta[b]furan-2-one is synthesized through various chemical reactions and is primarily utilized in pharmaceutical and medicinal research due to its potential biological activities. The specific properties and potential applications of this compound are contingent upon its purity, stability, and interactions with other substances.
Uses
Used in Pharmaceutical and Medicinal Research:
[3aR,4R(1E,3R),5R,6aS]-5-benzoyloxy-4-(3-hydroxyocten-1-yl)-hexahydro-2H-cyclopenta[b]furan-2-one is used as a compound in pharmaceutical and medicinal research for its potential biological activities. [3aR,4R(1E,3R),5R,6aS]-5-benzoyloxy-4-(3-hydroxyocten-1-yl)-hexahydro-2H-cyclopenta[b]furan-2-one's unique structure and properties make it a promising candidate for the development of new drugs and therapies.
Used in Chemical Synthesis:
In the chemical industry, [3aR,4R(1E,3R),5R,6aS]-5-benzoyloxy-4-(3-hydroxyocten-1-yl)-hexahydro-2H-cyclopenta[b]furan-2-one can be used as a key intermediate in the synthesis of more complex molecules, potentially leading to the development of novel pharmaceuticals, agrochemicals, or other specialty chemicals.
Used in Drug Delivery Systems:
Similar to other complex organic compounds, [3aR,4R(1E,3R),5R,6aS]-5-benzoyloxy-4-(3-hydroxyocten-1-yl)-hexahydro-2H-cyclopenta[b]furan-2-one may be employed in the development of drug delivery systems. Its unique structure could be utilized to improve the delivery, bioavailability, and therapeutic outcomes of various drugs, particularly in the context of targeted drug delivery or controlled release applications.
Used in Analytical Chemistry:
[3aR,4R(1E,3R),5R,6aS]-5-benzoyloxy-4-(3-hydroxyocten-1-yl)-hexahydro-2H-cyclopenta[b]furan-2-one's distinct chemical properties may also make it useful in analytical chemistry, where it could be employed as a reference material, a reagent, or a component in the development of new analytical methods or techniques.
Check Digit Verification of cas no
The CAS Registry Mumber 51705-58-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,1,7,0 and 5 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 51705-58:
(7*5)+(6*1)+(5*7)+(4*0)+(3*5)+(2*5)+(1*8)=109
109 % 10 = 9
So 51705-58-9 is a valid CAS Registry Number.
51705-58-9Relevant articles and documents
Synthesis of 15R-PGD2: A potential DP2 receptor agonist
Kim, Seongjin,Bellone, Sophie,Maxey, Kirk M.,Powell, William S.,Lee, Gue-Jae,Rokach, Joshua
, p. 1873 - 1876 (2007/10/03)
The first total synthesis of 15R-PGD2 3 was accomplished. The approach used in this report is also an efficient method to produce 15R-PGE 2. 15R-PGD2, a potential DP2 receptor agonist, could be an important novel tool for defining the role of this receptor in inflammatory diseases.
Stereocontrol in organic synthesis using silicon-containing compounds. A formal synthesis of prostaglandins controlling the stereochemistry at C-15 using a silyl-to-hydroxy conversion following a stereochemically convergent synthesis of an allylsilane
Fleming, Ian,Winter, Stephen B. D.
, p. 2687 - 2700 (2007/10/03)
Hydrosilylation of isoprene with chloro(diphenyl)silane gave (Z)-chloro(2-methylbut-2-enyl)-diphenylsilane 7. The cuprate reagent derived from this chloride underwent conjugate addition to methyl cinnamate 11, 1,2-silylcupration with hex-1-yne 16 and allene 18, and allylic displacement reactions with 1-vinylcyclohexyl acetate 20 and (Z)-1-cyclopentyloct-2-en-1-yl acetate 22. The silyl group in each of the products was converted into a hydroxy, with the removal of the 2-methylbut-2-enyl group taking place under much milder acidic conditions than those needed to remove the phenyl group from the dimethyl(phenyl)silyl group, and making this group suitable for the conversion of an allylsilane into an allyl alcohol. A stereospecifically anti conjugate displacement of the allylic benzoate group in (Z)-(1S,5R,6R,7R,1′S)-7-benzoyloxy-6-(1′-benzoyloxyoct-2′- enyl)-2-oxabicyclo[3.3.0]octan-3-one 52, and a stereospecifically syn conjugate displacement of the carbamate group in (Z)-(1S,5R,6R,7R,1′R)-7-benzoyloxy-6-(1′-N-phenylcarbamoyloxyoct- 2′-enyl)-2-oxabicyclo[3.3.0]octan-3-one 51, gave stereo-convergently the same allylsilane (1′ E,2″Z)-(1S,5S,6R,7R,3′S)-7-benzoyloxy-6-[3′-(2″- methylbut-2″-enyl)-diphenylsilyloct-1′-enyl]-2-oxabicyclo[3.3.0] octan-3-one 53. Silyl-to-hydroxy conversion gave the allyl alcohol (E)-(1S,5S,6R,7R,3′S)-7-benzoyloxy-6-(3′-hydroxyoct-1′-enyl)- 2-oxabicyclo[3.3.0]octan-3-one 54, having the relative and absolute stereochemistry at C-15 of the prostaglandins.
