51707-42-7

Basic information

• Product Name: Hydrazinecarboxamide, N-(3-chlorophenyl)-
• CAS NO: 51707-42-7
• Molecular Formula: C7H8ClN3O
• Molecular Weight: 185.613
• Mol File: 51707-42-7.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Hydrazinecarboxamide, N-(3-chlorophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Hydrazinecarboxamide, N-(3-chlorophenyl)-(51707-42-7)
• EPA Substance Registry System: Hydrazinecarboxamide, N-(3-chlorophenyl)-(51707-42-7)

Safety Data

• Hazardous Substances Data: 51707-42-7(Hazardous Substances Data)

Upstream product

• 2392-68-9 3-chlorophenyl-isothiocyanate 
• 2366-82-7 (3-chloro-phenyl)-carbamic acid-(2,2,2-trifluoro-ethyl ester) 
• 108-42-9 3-chloro-aniline 
• 2909-38-8 m-chlorophenyl isocyanate 
• 1967-27-7 (3-chlorophenyl)urea 

Downstream Products

• 80240-38-6 C₈H₆ClN₃O 
• 94064-08-1 1-[5-(3-chloro-anilino)-[1,3,4]oxadiazol-2-yl]-3-phenyl-urea 
• 527684-99-7 2',3',5'-tri-O-acetyl-2-[3-(3-chlorophenyl)aminocarbonyltriazene-1-yl]adenosine 
• 90110-29-5 2-N-(3-chlorophenyl)-1,3,4-oxadiazole-2,5-diamine 

Relevant articles and documents

Anticonvulsant and sedative-hypnotic activities of N-substituted isatin semicarbazones

A series of N-methyl/acetyl, 5-(un)-substituted isatin-3-semicarbazones were screened for anticonvulsant and sedative-hypnotic activities. The results revealed that protection was obtained in all the screens i.e., MES, scPTZ, and scSTY. Compounds 2, 4, 6, 10 but not 1 and 3 showed low neurotoxicity when compared to clinically used drugs. Compounds 5, 7, 8 and 9 were completely non-toxic. Compound 6 showed good activity in the rat oral MES screen. Among all the compounds, 3 and 6 emerged as the most active compounds as indicated by the protection they exhibit in MES, scSTY, and scPTZ screens. All the compounds showed significant sedativehypnotic activity.

Gold-Catalyzed Functionalization of Semicarbazides with Terminal Alkynes to Achieve Substituted Semicarbazones

Gold-catalyzed functionalization of semicarbazides (ArNHCONHNH2) with various terminal alkynes R2C≡CH (R2 = Alk or Ar) in the presence of Ph3PAuNTf2 (3 mol-%) grants a range of substituted semicarbazo

Facile one-pot synthesis of 4-substituted semicarbazides

A diverse library of twenty-five 4-mono- and disubstituted semicarbazides was prepared in a one-pot two-step approach. The method includes formation of a carbamate from bis(2,2,2-trifluoroethyl)carbonate or 2,2,2-trifluoroethylchloroformate and a primary or secondary amine and subsequent interaction of the carbamate with hydrazine to result in a semicarbazide. The approach allowed to obtain 4-substituted semicarbazides on a large scale in good yield and high purity. This journal is