51718-80-0

Basic information

• Product Name: METHYL 2-(1H-IMIDAZOL-4-YL)ACETATE HYDROCHLORIDE
• Synonyms: METHYL 2-(1H-IMIDAZOL-4-YL)ACETATE HYDROCHLORIDE;Methyl 2-(1H-iMidazol-4-yl)acetate HCl;Methyl 2-(1H-iMidazol-5-yl)acetate hydrochloride;methyl 2-(1H-imidazol-4-yl)acetate
• CAS NO: 51718-80-0
• Molecular Formula: C₆H₈N₂O₂*ClH
• Molecular Weight: 176.6
• Mol File: 51718-80-0.mol
• Article Data: 24

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: METHYL 2-(1H-IMIDAZOL-4-YL)ACETATE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 2-(1H-IMIDAZOL-4-YL)ACETATE HYDROCHLORIDE(51718-80-0)
• EPA Substance Registry System: METHYL 2-(1H-IMIDAZOL-4-YL)ACETATE HYDROCHLORIDE(51718-80-0)

Safety Data

• Hazardous Substances Data: 51718-80-0(Hazardous Substances Data)

Usage

Description

METHYL 2-(1H-IMIDAZOL-4-YL)ACETATE HYDROCHLORIDE is a chemical compound belonging to the imidazole family, characterized by its unique structure and properties. It is a potent non-thiol inhibitor of farnesyl protein transferase, which plays a significant role in various cellular processes.

Uses

Used in Pharmaceutical Industry:
METHYL 2-(1H-IMIDAZOL-4-YL)ACETATE HYDROCHLORIDE is used as a research compound for the development of potential therapeutic agents targeting farnesyl protein transferase. Its ability to inhibit this enzyme makes it a valuable tool in the study and treatment of various diseases associated with the enzyme's dysregulation.
Used in Analytical Chemistry:
METHYL 2-(1H-IMIDAZOL-4-YL)ACETATE HYDROCHLORIDE is used as an analytical reagent in the identification and quantification of farnesyl protein transferase inhibitors. Its specificity for the enzyme allows researchers to better understand the interactions between the compound and the enzyme, which can lead to the development of more effective drugs.

Upstream product

• 67-56-1 methanol 
• 3251-69-2 imidazole-4-acetic acid hydrochloride 
• 645-65-8 2-(1H-imidazol-4-yl)acetic acid 

Downstream Products

• 497159-97-4 methyl {1-[(4-methylphenyl)sulfonyl]-1H-imidazol-4-yl}acetate 
• 858954-56-0 (1⁽³⁾H-imidazol-4-yl)-acetic acid hydrazide 
• 497159-98-5 dimethyl 2-{1-[(4-methylphenyl)sulfonyl]-1H-imidazol-4-yl}malonate 
• 1027056-58-1 3-(6-amino-pyridin-3-yl)-2-(1-benzyl-1H-imidazol-4-yl)-propionic acid ethyl ester 
• 497159-99-6 dimethyl 2-({6-[(tert-butoxycarbonyl)amino]pyridin-3-yl}methyl)-2-{1-[(4-methylphenyl)sulfonyl]-1H-imidazol-4-yl}malonate 
• 145133-11-5 methyl [1-(triphenylmethyl)-1H-imidazol-4-yl]acetate 
• 179025-88-8 1-(4-Nitrophenylmethyl)-1H-imidazol-4-ylacetic acid methyl ester 
• 872-82-2 2-(1H-imidazol-4-yl)ethanol 
• 1610728-66-9 N,N'-(5,5'-((1S,3S)-cyclohexane-1,3-diyl)bis(1,3,4-thiadiazole-5,2-diyl))bis(2-(1H-imidazol-4-yl)acetamide) 

Relevant articles and documents

Esters of 4 hydroxymethylimidazole and 4 imidazoleacetic acid

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COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND USES AS GLUTAMINASE INHIBITORS FOR TREATING CANCERS THEREOF

Provided are compounds of formula (I), wherein X, Y, Z, W, m, n, o, p, R1, R2 and R6 are defined as in the description. Pharmaceutical compositions and uses as glutaminase inhibitors for treating cancers thereof are also provided.

IMIDAZOLE DERIVATIVES USED AS TAFIA INHIBITORS

The present invention relates to compounds of formula (I) which are inhibitors of the activated thrombin-activatable fibrinolysis inhibitor. The compounds of formula (I) are suited for producing medicaments for the prevention and treatment of diseases acc