51745-28-9Relevant articles and documents
Online structural elucidation of alkaloids and other constituents in crude extracts and cultured cells of Nandina domestica by combination of LC-MS/MS, LC-NMR, and LC-CD analyses
Iwasa, Kinuko,Takahashi, Teturo,Nishiyama, Yumi,Moriyasu, Masataka,Sugiura, Makiko,Takeuchi, Atsuko,Tode, Chisato,Tokuda, Harukuni,Takeda, Kazuyoshi
, p. 1376 - 1385 (2008)
The combination of NMR, MS, and CD data permitted the structural elucidation including the absolute configuration of the known alkaloids and unknown components in the extract matrix solution of Nandina domestica without isolation and sample purification p
Enantioselective synthesis of chiral tetrahydroisoquinolines by iridium-catalyzed asymmetric hydrogenation of enamines
Yan, Pu-Cha,Xie, Jian-Hua,Hou, Guo-Hua,Wang, Li-Xin,Zhou, Qi-Lin
supporting information; experimental part, p. 3243 - 3250 (2010/04/24)
Chiral iridium complexes based on spiro phosphoramidite ligands are demonstrated to be highly efficient catalysts for the asymmetric hydrogenation of unfunctionalized enamines with an exocyclic double bond. In combination with excess iodine or potassium i
Chiral Acetylenic Sulfoxide in Enantioselective Synthesis of Tetrahydroisoquinoline and Tetrahydro-β-carboline Alkaloids. Total Synthesis of (R)-(+)-Carnegine and (R)-(+)-Tetrahydroharman
Lee, Albert W. M.,Chan, Wing Hong,Tao, Yi,Lee, Yu Kai
, p. 477 - 482 (2007/10/02)
Michael addition of 2-(3,4-dimethoxyphenyl)ethylamine 3 or tryptamine 4 onto chiral acetylenic sulfoxides 2 followed by acid induced cyclization afforded the basic alkaloid skeleton of tetraisoquinoline and tetrahydro-β-carboline in high to moderate diastereoselectivity.Optically pure (R)-(+)-carnegine and (R)-(+)-tetrahydroharman have been synthesized.