51796-81-7

Basic information

• Product Name: 2-Bromo-4,6-dinitrochlorobenzene
• Synonyms: 1-Chloro-2-bromo-4,6-dinitrobenzene;2-Bromo-1-chloro-4,6-dinitrobenzene;2-Bromo-4,6-dinitrochlorobenzene;1-bromo-2-chloro-3,5-dinitrobenzene
• CAS NO: 51796-81-7
• Molecular Formula: C₆H₂BrClN₂O₄
• Molecular Weight: 281.44808
• Mol File: 51796-81-7.mol
• Article Data: 4

Chemical Properties

• Melting Point: 61-62℃
• Appearance: /
• CAS DataBase Reference: 2-Bromo-4,6-dinitrochlorobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Bromo-4,6-dinitrochlorobenzene(51796-81-7)
• EPA Substance Registry System: 2-Bromo-4,6-dinitrochlorobenzene(51796-81-7)

Safety Data

• Hazardous Substances Data: 51796-81-7(Hazardous Substances Data)

Upstream product

• 2316-50-9 2-bromo-4,6-dinitrophenol 
• 98-59-9 p-toluenesulfonyl chloride 
• 91-66-7 N,N-diethylaniline 
• 100-00-5 4-chlorobenzonitrile 
• 97-00-7 1-chloro-2,4-dinitro-benzene 

Downstream Products

• 2367-75-1 5-bromo-1,3-dinitro-4-fluorobenzene 
• 1817-73-8 2-bromo-4,6-dinitroaniline 
• 57072-72-7 (2-bromo-4,6-dinitro-phenyl)-hydrazine 
• 91330-95-9 (2-bromo-4,6-dinitro-phenyl)-phenyl-amine 
• 26103-32-2 1,3-Dinitro-phenoxazin 
• 109019-06-9 N-(2-bromo-4,6-dinitro-phenyl)-N'-phenyl-hydrazine 
• 56205-34-6 3-(2-bromo-4,6-dinitro-phenyl)-2-thioxo-thiazolidin-4-one 
• 68142-45-0 5-benzylidene-3-(2-bromo-4,6-dinitro-phenyl)-2-thioxo-thiazolidin-4-one 
• 68142-29-0 3-(2-bromo-4,6-dinitro-phenyl)-5-(4-methoxy-benzylidene)-2-thioxo-thiazolidin-4-one 
• 3396-34-7 morpholine-4-carbodithioic acid 2-bromo-4,6-dinitro-phenyl ester 
• 68142-61-0 5-(Z)-benzo[1,3]dioxol-5-ylmethylene-3-(2-bromo-4,6-dinitro-phenyl)-2-thioxo-thiazolidin-4-one 
• 93308-01-1 2-Brom-4,6-dinitro-2'-amino-4'-methyl-diphenylamin 
• 2431-16-5 N,N-Diethyl-dithiocarbamidsaeure-<6-brom-2,4-dinitro-phenylester> 
• 57221-26-8 p-Chlorophenyl-2-bromo-4,6-dinitrophenyl-sulfid 

Relevant articles and documents

CYCLIC COMPOUNDS AND USES THEREOF

The invention generally relates to substituted benzothiophenyl, substituted benzothiazolyl, substituted indolyl and substituted benzoimidazolyl compounds and, more particularly, to a compound represented by Structural Formula I: or a pharmaceutically acceptable salt thereof, wherein the variables are as defined and described herein. The invention also includes the synthesis and use of a compound of Structural Formula I, or a pharmaceutically acceptable salt or composition thereof, e.g., in the treatment of a disease or disorder selected from cancer (e.g., lymphoma, such as mantle cell lymphoma), a neurodegenerative disease, inflammatory diseases or an autoimmune system disease (e.g., a T-Cell mediated autoimmune disesase).

Preparation of substituted methyl o-nitrophenyl sulfides

The nucleophilic substitution of substituted o-nitrochlorobenzenes with substituted methanethiolates, catalysed with triethylamine or pyridine, has been used to prepare a series of appropriately substituted methyl-o- nitrophenylsulfides. The prepared compounds were identified by their 1H- and 13C-NMR spectra. The base catalysed ring closure of methyl 2-(methoxycarbonylmethylsulfanyl)-3,5-dinitrobenzenecarboxylate only results in an attack of carbanion on the ester group, not on a nitro group as with the other compounds prepared. The cyclisation product is methyl 3-hydroxy-5,7-dinitro-benzo[b]thiophene-2-carboxylate (11).