5183-61-9Relevant articles and documents
Oxidative dearomatization/intramolecular Diels-Alder cycloaddition cascade for the syntheses of (±)-atisine and (±)-isoazitine
Liu, Xiao-Yu,Cheng, Hang,Li, Xiao-Huan,Chen, Qiao-Hong,Xu, Liang,Wang, Feng-Peng
, p. 1411 - 1417 (2012)
A convergent and efficient formal synthesis of (±)-atisine has been accomplished. The synthetic strategy is to efficiently construct the bicyclo[2.2.2]octane ring moiety by an oxidative dearomatization/intramolecular Diels-Alder cycloaddition cascade. The first total synthesis of another atisine-type C20-diterpenoid alkaloid, (±)-isoazitine, has also been achieved employing the same strategy.
METHODS OF TREATING DISORDER
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Page/Page column 29, (2008/06/13)
Compound of formula (I) and methods of treating disorders by administering a compound of formula (I) are described herein. Examples of disorders include neoplastic disorders, fat-cell related disorders, neurodegenerative disorders, and metabolic disorders