51830-50-3

Basic information

• Product Name: P-(TOLYLTHIO)ACETALDEHYDE DIETHYL ACETAL
• Synonyms: P-(TOLYLTHIO)ACETALDEHYDE DIETHYL ACETAL;4-(METHYLPHENYLTHIO)ACETALDEHYDE DIETHYL ACETAL
• CAS NO: 51830-50-3
• Molecular Formula: C₁₃H₂₀O₂S
• Molecular Weight: 240.36
• EINECS: -0
• Mol File: 51830-50-3.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 106-108°C 0,25mm
• Flash Point: 106-108°C/0.25m
• Appearance: /
• Density: 1.03g/cm³
• Vapor Pressure: 0.000837mmHg at 25°C
• Refractive Index: 1.5200
• Storage Temp.: 2-8°C
• BRN: 1964544
• CAS DataBase Reference: P-(TOLYLTHIO)ACETALDEHYDE DIETHYL ACETAL(CAS DataBase Reference)
• NIST Chemistry Reference: P-(TOLYLTHIO)ACETALDEHYDE DIETHYL ACETAL(51830-50-3)
• EPA Substance Registry System: P-(TOLYLTHIO)ACETALDEHYDE DIETHYL ACETAL(51830-50-3)

Safety Data

• Safety Statements: S24/25:Avoid contact with skin and eyes.
• Hazardous Substances Data: 51830-50-3(Hazardous Substances Data)

Usage

General Description

P-(Tolylthio)acetaldehyde Diethyl Acetal is a complex chemical compound often used in a wide variety of industrial applications. Although there is little general information available, it is known to be related to organosulfur compounds, an organic compound containing sulfur. They are often associated with a strong smell. The structure of this compound suggests it may have specific reactivity that makes it useful in chemical synthesis. As with any chemical compound, proper handling and safety measures should be followed when using P-(Tolylthio)acetaldehyde Diethyl Acetal due to its potential for toxicity or harmful reactions. Detailed information about this compound can be obtained from a material safety data sheet (MSDS) or through direct contact with the manufacturer or supplier.

InChI:InChI=1/C13H20O2S/c1-4-14-13(15-5-2)10-16-12-8-6-11(3)7-9-12/h6-9,13H,4-5,10H2,1-3H3

Upstream product

• 10486-08-5 sodium p-thiocresolate 
• 2032-35-1 Bromoacetaldehyde diethyl acetal 
• 621-62-5 chloroacetaldehyde diethyl acetal 
• 106-45-6 para-thiocresol 

Downstream Products

• 91969-68-5 cis-1-ethoxy-2-p-tolylsulfanyl-ethene 
• 91969-68-5 trans-1-ethoxy-2-p-tolylsulfanyl-ethene 
• 41208-03-1 2-(4-tolylthio)acetaldehyde 
• 93734-73-7 p-tolylsulfanyl-acetaldehyde-(2,4-dinitro-phenylhydrazone) 
• 14315-14-1 5-methylthianaphthene 
• 155873-21-5 2-{2-[(4-methylphenyl)thio]ethylidene} thiosemicarbazone 
• 736931-74-1 5-(toluene-4-sulfonyl)-thiazol-2-ylamine 
• 873401-59-3 N-[5-(toluene-4-sulfonyl)-thiazol-2-yl]-acetamide 
• 6739-66-8 (toluene-4-sulfony)acetaldehyde 
• 6461-80-9 (toluene-4-sulfonyl)-acetaldehyde semicarbazone 
• 88791-08-6 7-methoxybenzothiophene 
• 193965-35-4 (7-methoxy-1-benzothiophen-2-yl)boronic acid 

Relevant articles and documents

Benzyne 1,2,4-Trisubstitution and Dearomative 1,2,4-Trifunctionalization

Both 1,2,4-trisubstitution and dearomative 1,2,4-trifunctionalization of benzyne have been accomplished from sulfoxides bearing a penta-2,4-dien-1-yl moiety. These cascade transformations proceed through a benzyne insertion into the S═O bond and an uncommon regiospecific anionic [4,5]-sigmatropic rearrangement, furnishing a C-O, C-S, and C-C bond on the C1-, C2-, and C4-position of a benzene ring, respectively. This study showcases new cascade benzyne reaction modes involving both distal C-H bond functionalization and dearomatization.

Dioxazolones as masked ester surrogates in the Pd(ii)-catalyzed direct C-H arylation of 6,5-fused heterocycles

A simple and effective Pd(ii)-catalyzed regioselective C(2)-H arylation of 6,5-fused heterocycles with dioxazolones as a masked ester surrogate under mild conditions is reported. The significance of the arylation is highlighted by the new reactivity demonstrated in dioxazolones via proximal C-H activation of the cyclic carbonate of the hydroxamic acid functionality under protic conditions.

NOVEL INHIBITORS OF BETA-LACTAMASE

This invention provides novel β-lactamase inhibitors of the aryl- and heteroarylsulfonamidomethylphosphonate monoester class having nitrogen-based cations or quarternary ammonium groups. The compounds inhibit three classes of β-lactamases and synergize the antibacterial effects of β-lactam antibiotics (e.g., imipenem and ceftazidime) against those micro-organisms normally resistant to the β-lactam antibiotics as a result of the presence of the β-lactamases. Formula (I) or pharmaceutically acceptable salt thereof.