51839-12-4

Basic information

• Product Name: 3',5'-Dimethylbiphenyl-2-amine
• Synonyms: 3',5'-Dimethylbiphenyl-2-amine
• CAS NO: 51839-12-4
• Molecular Formula: C₁₄H₁₅N
• Molecular Weight: 197.28
• Mol File: 51839-12-4.mol
• Article Data: 11

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3',5'-Dimethylbiphenyl-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 3',5'-Dimethylbiphenyl-2-amine(51839-12-4)
• EPA Substance Registry System: 3',5'-Dimethylbiphenyl-2-amine(51839-12-4)

Safety Data

• Hazardous Substances Data: 51839-12-4(Hazardous Substances Data)

Upstream product

• 51839-09-9 3,5-dimethyl-2’-nitrobiphenyl 
• 22445-41-6 3,5-dimethylphenyl iodide 
• 108-69-0 3,5-dimethylaminoaniline 
• 615-36-1 2-bromoaniline 
• 325142-93-6 2-(3,5-dimethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 172975-69-8 3,5-dimethylphenyl boronic acid 
• 556-96-7 5-bromo-1,3-xylene 
• 873-75-6 4-bromobenzenemethanol 

Downstream Products

• 71903-08-7 2-Amino-2'-(3',5'-dimethylbiphenyl-2-ylazo)biphenyl 
• 1178866-11-9 6-(3,4-dimethoxyphenyl)-7,9-dimethylphenanthridine 

Relevant articles and documents

Additive-free radical cascade reaction of oxime esters: Synthesis of pyrroline-functionalized phenanthridines

A variety of dihydropyrrole-functionalized phenanthridines were efficiently synthesized by the metal-free, radical cascade cyclization reaction of 2-isocyanobiphenyls with γ,δ- unsaturated oxime esters. The C-N/C-C/C-C bonds were formed via the oil bath method in a one-pot procedure with broad substrate applicability. The radical process was supported by kinetic isotope effect studies and radical inhibition studies.

Metal- and additive-free cascade trifluoroethylation/cyclization of organic isoselenocyanates by phenyl(2,2,2-trifluoroethyl)iodonium triflate

A novel and convenient cascade trifluoroethylation/cyclization of organic isoselenocyanates by phenyl(2,2,2-trifluoroethyl)iodonium triflate is reported. A series of 2-isoselenocyanobiaryls and aryl alkyl isoselenocyanates reacted with phenyl(2,2,2-trifluoroethyl)iodonium triflate in CH2Cl2 at 40 °C under metal- and additive-free conditions for 3 h to provide the corresponding trifluoroethylselenolated phenanthridines and 3,4-dihydroisoquinoline derivatives in good to excellent yields. The reaction represents the first general approach to access trifluoroethylselenolated phenanthridines and 3,4-dihydroisoquinolines from organic isoselenocyanates.

MeOTf- and TBD-Mediated Carbonylation of ortho-Arylanilines with CO2 Leading to Phenanthridinones

Carbonylation of o-arylanilines utilizing CO2 as a carbonyl source for the synthesis of important phenanthridinones with a free (NH)-lactam motif has been described under metal-free condition. A range of o-arylanilines were transformed to the corresponding phenanthridinones in high yields.