5185-54-6

Basic information

• Product Name: 2,6-DICHLORO-4-PHENYL-QUINAZOLINE
• Synonyms: 2,6-DICHLORO-4-PHENYL-QUINAZOLINE
• CAS NO: 5185-54-6
• Molecular Formula: C₁₄H₈Cl₂N₂
• Molecular Weight: 275.13
• Mol File: 5185-54-6.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 378.2°C at 760 mmHg
• Flash Point: 214.4°C
• Appearance: /
• Density: 1.381g/cm³
• Vapor Pressure: 1.39E-05mmHg at 25°C
• Refractive Index: 1.672
• CAS DataBase Reference: 2,6-DICHLORO-4-PHENYL-QUINAZOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-DICHLORO-4-PHENYL-QUINAZOLINE(5185-54-6)
• EPA Substance Registry System: 2,6-DICHLORO-4-PHENYL-QUINAZOLINE(5185-54-6)

Safety Data

• Hazard Codes: Xi,T
• Statements: 25-37/38-41
• Safety Statements: 26-39-45
• HazardClass: IRRITANT
• Hazardous Substances Data: 5185-54-6(Hazardous Substances Data)

Usage

General Description

2,6-dichloro-4-phenyl-quinazoline is a chemical compound with the molecular formula C15H9Cl2N3. It is a nitrogen-containing heterocyclic compound with two chlorine atoms, a phenyl group, and a quinazoline ring structure. 2,6-DICHLORO-4-PHENYL-QUINAZOLINE has been investigated for its potential pharmaceutical properties, including its potential as an anticancer and antimicrobial agent. It has also been studied for its potential use in organic synthesis as a building block for creating new compounds. The compound's structure and properties make it a subject of interest for research in medicinal chemistry and chemical synthesis.

InChI:InChI=1/C14H8Cl2N2/c15-10-6-7-12-11(8-10)13(18-14(16)17-12)9-4-2-1-3-5-9/h1-8H

Upstream product

• 4797-43-7 6-chloro-4-phenyl-2-quinazolinone 
• 719-59-5 5-chloro-2-aminobenzophenone 
• 4797-43-7 6-chloro-4-phenylquinazolin-2-ol 

Downstream Products

• 57370-20-4 6-Chlor-2-hydrazino-4-phenyl-chinazolin 
• 100693-28-5 6-Chloro-2-(3,5-dimethyl-pyrazol-1-yl)-4-phenyl-quinazoline 
• 100672-14-8 2-(6-Chloro-4-phenyl-quinazolin-2-yl)-5-methyl-2,4-dihydro-pyrazol-3-one 
• 100672-17-1 6-Chloro-4-phenyl-2-(3,3,5-trimethyl-2,3-dihydro-pyrazol-1-yl)-quinazoline 
• 100672-19-3 5-Amino-2-(6-chloro-4-phenyl-quinazolin-2-yl)-1,2-dihydro-pyrazol-3-one 
• 100672-22-8 1-(6-Chloro-4-phenyl-quinazolin-2-yl)-4-phenyl-1H-pyrazol-3-ylamine 
• 57370-21-5 7-chloro-1-methyl-5-phenyl-[1,2,4]triazolo[4,3-a]quinazoline 
• 67095-57-2 (6-chloro-4-phenyl-quinazolin-2-yl)-(2,2-dimethoxy-ethyl)-amine 
• 64820-61-7 7-chloro-5-phenyl-tetrazolo[1,5-a]quinazoline 
• 919955-17-2 6-chloro-2-furfurylamino-4-phenylquinazoline 
• 1026768-88-6 6-chloro-2-ethoxycarbonylmethylamino-4-phenylquinazoline 
• 1026768-87-5 6-chloro-2-methoxyamino-4-phenylquinazoline 
• 1026768-90-0 6-chloro-2-formamido-4-phenylquinazoline 
• 1026769-15-2 6-chloro-2-(2-hydroxyethylthio)-4-phenylquinazoline 

Relevant articles and documents

4-ARYLQUINAZOLINE DERIVATIVES AS INHIBITORS OF METHIONINE ADENOSYLTRANSFERASE 2A

The invention relates to certain derivatives of 4-arylquinazoline formula (I) which are inhibitors of methionine adenosyltransferase 2A (MAT2A). The invention also relates to pharmaceutical compositions comprising such compounds and methods of treating diseases that can be treated by inhibition of MAT2A such as cancer, including cancers characterized by reduced or no activity of methylthioadenosine phosphorylase (MTAP).

Synthesis and Antiinflammatory Activity of 4-Aryl-2-(1'-pyrazolyl)quinazolines

4-Aryl-2-hydrazinoquinazolines (III) on condensation with acetylacetone, ethyl acetoacetate, mesityl oxide, ethyl cyanoacetate and α-formylphenylacetonitrile afford the corresponding 4-aryl-2-(1'-pyrazolyl)quinazolines (IV, V, VIII, XII and XVI).These com

Synthesis of 5-aryl-12H-quinazolino[3,2-a]quinazolin-12-ones as antiinflammatory agents

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