5186-54-9

Basic information

• Product Name: 5-(3-nitrobenzoyl)-2-(pyridin-2-yl)-1H-isoindole-1,3(2H)-dione
• Synonyms: 1H-isoindole-1,3(2H)-dione, 5-(3-nitrobenzoyl)-2-(2-pyridinyl)-; 5-(3-Nitrobenzoyl)-2-(pyridin-2-yl)-1H-isoindole-1,3(2H)-dione
• CAS NO: 5186-54-9
• Molecular Formula: C₉H₄N₂O₃
• Molecular Weight: 373.3184
• Mol File: 5186-54-9.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 639.2°C at 760 mmHg
• Flash Point: 340.4°C
• Density: 1.493g/cm³
• Vapor Pressure: 3.1E-16mmHg at 25°C
• Refractive Index: 1.699
• CAS DataBase Reference: 5-(3-nitrobenzoyl)-2-(pyridin-2-yl)-1H-isoindole-1,3(2H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(3-nitrobenzoyl)-2-(pyridin-2-yl)-1H-isoindole-1,3(2H)-dione(5186-54-9)
• EPA Substance Registry System: 5-(3-nitrobenzoyl)-2-(pyridin-2-yl)-1H-isoindole-1,3(2H)-dione(5186-54-9)

Safety Data

• Hazardous Substances Data: 5186-54-9(Hazardous Substances Data)

Upstream product

• 5725-79-1 3-amino-4-hydroxy-2H-chromen-2-one 
• 1076-38-6 4-hydroxy[1]benzopyran-2-one 
• 7782-77-6 cis-nitrous acid 
• 75020-20-1 9-Oxo-1H,9H-benzopyrano<2,3-d>-v-triazole 
• 941-55-9 4-toluenesulfonyl azide 
• 4438-85-1 3H-chromene-2,4-dione 

Downstream Products

• 109797-45-7 3-[2'-cyclohexenyl]-4-hydroxy-1-benzopyran-2(H)-one 
• 94302-75-7 4-(4-methoxyphenyl)-4-hydroxycoumarin 
• 6619-24-5 4-hydroxy-3-<(4-methylphenyl)methyl>-2H-1-benzopyran-2-one 
• 73791-11-4 3-<2,5-Dimethyl-phenyl>-4-hydroxy-cumarin 
• 15074-18-7 3-benzyl-4-hydroxycoumarin 
• 73791-18-1 4-hydroxy-3-o-tolyl-chromen-2-one 
• 73791-19-2 4-hydroxy-3-(p-tolyl)-1-benzopyran-2-one 
• 1786-05-6 4-hydroxy-3-phenylcoumarin 

Relevant articles and documents

Studies on V-triazoles. Part III. On the nitration of 9-oxo-1H,9H-benzopyrano[2,3-d]-v-triazole

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A 'sulfonyl-azide-free' (SAFE) aqueous-phase diazo transfer reaction for parallel and diversity-oriented synthesis

Diazo transfer reactions are notoriously associated with the use of potentially explosive sulfonyl azides. The first 'sulfonyl-azide-free' (SAFE) protocol for producing diazo compounds from their active-methylene precursors via the Regitz diazo transfer reaction was developed and has displayed a remarkable substrate scope. It can be applied to generating arrays of diazo compounds for further evolution via combinatorial chemistry and a range of scaffold-generating transformations.

Direct ionic liquid promoted organocatalyzed diazo-transfer reactions: diversity-oriented synthesis of diazo-compounds

A practical and novel ionic liquid promoted organocatalytic selective diazo-transfer process for the synthesis of highly substituted diazo-compounds in high yields is reported. The ionic liquid can be reused without affecting the reaction rates or yields over five runs.