5187-71-3Relevant articles and documents
A Synthetic Approach to Furanocembranolides
Kondo, Akihiro,Ochi, Takeshi,Iio, Hideo,Tokoroyama, Takashi,Siro, Motoo
, p. 1491 - 1494 (1987)
The furanocembranoid skeleton of lophotoxin-type has been constructed efficiently by a method utilizing the formation reaction of a furan ring for the macrocyclization.
TETRAHYDRONAPHTHALENE DERIVATIVES THAT INHIBIT MCL-1 PROTEIN
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Page/Page column 178, (2016/03/22)
Provided herein are myeloid cell leukemia 1 protein (Mcl-1) inhibitors, methods of their preparation, related pharmaceutical compositions, and methods of using the same. For example, provided herein are compounds of Formula I, (I) and pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the compounds. The compounds and compositions provided herein may be used, for example, in the treatment of diseases or conditions, such as cancer.
Diversity-oriented synthesis of hydrazine-derived compounds from amino isocyanates generated in situ
Clavette, Christian,Vincent Rocan, Jean-Francois,Beauchemin, Andre M.
supporting information, p. 12705 - 12708 (2013/12/04)
Behind the mask: Nitrogen-substituted isocyanates are rare and their synthetic potential is virtually untapped. Simple masked precursors can form amphoteric amino isocyanate intermediates in situ, and allows the synthesis of complex hydrazine derivatives upon addition with amines. This reactivity was used in a cascade substitution/hydroamination sequence, and in the assembly of azadipeptide analogues. Copyright