51876-19-8

Basic information

• Product Name: 4H-1-Benzopyran-4-one,5,7,8-trihydroxy-2- (4-methoxyphenyl)-
• CAS NO: 51876-19-8
• Molecular Weight: 300.268
• Mol File: 51876-19-8.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 4H-1-Benzopyran-4-one,5,7,8-trihydroxy-2- (4-methoxyphenyl)- (CAS DataBase Reference)
• NIST Chemistry Reference: 4H-1-Benzopyran-4-one,5,7,8-trihydroxy-2- (4-methoxyphenyl)- (51876-19-8)
• EPA Substance Registry System: 4H-1-Benzopyran-4-one,5,7,8-trihydroxy-2- (4-methoxyphenyl)- (51876-19-8)

Safety Data

• Hazardous Substances Data: 51876-19-8(Hazardous Substances Data)

Upstream product

• 480-44-4 5,7-dihydroxy-2-(4'-methoxyphenyl)-4H-1-benzopyran-4-one 
• 41440-05-5 isoscutellarein 
• 21919-71-1 8-Hydroxy-5,7-dimethoxy-2-(4-methoxy-phenyl)-chromen-4-one 
• 21919-66-4 2,30dihydroxy-4,6-dimethoxyacetophenone 
• 54299-57-9 3-benzyloxy-2-hydroxy-4,6-dimethoxyacetophenone 
• 89456-13-3 2,3-bis(benzyloxy)-4,6-dimethoxyacetophenone 
• 89456-14-4 1-(3-Benzyloxy-2-hydroxy-4,6-dimethoxy-phenyl)-3-(4-methoxy-phenyl)-propane-1,3-dione 
• 89456-21-3 4-Methoxy-benzoic acid 2-acetyl-6-benzyloxy-3,5-dimethoxy-phenyl ester 

Downstream Products

• 100-09-4 4-methoxybenzoic acid 
• 65501-87-3 5,7-dihydroxy-8-methoxy-2-(4-methoxyphenyl)-4H-chromen-4-one 
• 89456-41-7 5,8-dihydroxy-7-methoxy-2-(4-methoxyphenyl)-4-benzopyrone 

Relevant articles and documents

Flavonoids from Stachys annua Growing in Azerbaijan

The new acylated flavonoid bioside 4′-O-methylisoscutellarein-7-O-[4-O-acetyl]allopyranosyl-(1→2)-glucopyranoside (1) was isolated from the aerial parts of Stachys annua L. (Lamiaceae). Subterranean organs yielded for the first time 4′-O-methylisoscutella

Biologically Active Compounds from Chamaenerion angustifolium and Stachys annua Growing in Azerbaidzhan

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Studies of the Selective O-Alkylation and Dealkylation of Flavonoids. VI. Demethylation of 8-Hydroxy-5,7-dimethoxyflavones with Anhydrous Aluminum Chloride or Bromide in Acetonitrile

The demethylation of seven 8-hydroxy-5,7-dimethoxyflavones with anhydrous aluminum chloride or bromide in acetonitrile was studied and the following results were obtained. (1) Anhydrous aluminum chloride in acetonitrile selectively split the 5-methoxyl group without cleavage of the 7-methoxyl group, and seven 5,8-dihydroxy-7-methoxy-flavones were quantitatively synthesized by the demethylation. (2) In the demethylation with anhydrous aluminum bromide, the 5- and 7-methoxyl groups on 4',5,7-trimethoxy- and 3',4',5,7-tetramethoxy-8-hydroxyflavone were selectively split to give the corresponding 5,7,8-trihydroxyflavones in good yield.However, the demethylation was not accessible to the synthesis of 5,7,8-trihydroxy-3',4',5'-trimethoxyflavone, 4',5,7,8-tetrahydroxy-3'-methoxy-, and 3',5,7,8-tetrahydroxy-4'-methoxyflavone, because of the cleavage of the methoxyl groups on the B ring.The synthesized flavones were employed for the identification of the two natural flavones, which were proposed to be 4',5,8-trihydroxy-7-methoxyflavone and 4',5,8-trihydroxy-3',7-dimethoxyflavone.The former, salvitin, was revised to 4',5,7-trihydroxy-6-methoxyflavone and the latter seemed to be 4',5,7-trihydroxy-3',8-dimethoxyflavone.