519-57-3 Usage
Uses
Different sources of media describe the Uses of 519-57-3 differently. You can refer to the following data:
1. Sulochrin is a fungal metabolite isolated from a number of Aspergillus and Penicillium sp.. An anti-angiogenic agent, sulochrin inhibits VEGF leading to inhibition of capillary-like tube formation of human umbilical vein endothelial cells. Sulochrin also inhibits eosinophil activation and chemotaxis.
2. Sulochrin is an inhibitor of the degranulation, activation and chemotaxis of eosinophils.
Check Digit Verification of cas no
The CAS Registry Mumber 519-57-3 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,1 and 9 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 519-57:
(5*5)+(4*1)+(3*9)+(2*5)+(1*7)=73
73 % 10 = 3
So 519-57-3 is a valid CAS Registry Number.
InChI:InChI=1/C17H16O7/c1-8-4-11(19)15(12(20)5-8)16(21)14-10(17(22)24-3)6-9(18)7-13(14)23-2/h4-7,18-20H,1-3H3
519-57-3Relevant articles and documents
Effects of ortho-substituent groups of sulochrin on inhibitory activity to eosinophil degranulation
Ohashi, Hiroshi,Ueno, Akihiro,Nakao, Toyoo,Ito, Junko,Kimura, Kaname,Ishikawa, Masaharu,Kawai, Hiroyuki,Iijima, Hiroshi,Osawa, Tatsushi
, p. 1945 - 1948 (2007/10/03)
Sulochrin, a metabolite of fungi, has been shown to have an inhibitory activity to eosinophil degranulation. A series of sulochrin derivatives substituted at ortho-positions to the 10-carbonyl group was examined the activity. The importance of alkylester
