519148-48-2 Usage
Uses
CJ 033466 is a partial, potent, and selective SR-4 agonist.
Biological Activity
Potent and selective 5-HT 4 partial agonist (EC 50 = 0.927 nM). Displays > 1000-fold selectivity for 5-HT 4 over other 5-HT and D 2 receptors. Exhibits gastroprokinetic effects in vivo following oral administration. Weakly blocks hERG (IC 50 = 2.6 μ M).
Check Digit Verification of cas no
The CAS Registry Mumber 519148-48-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,1,9,1,4 and 8 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 519148-48:
(8*5)+(7*1)+(6*9)+(5*1)+(4*4)+(3*8)+(2*4)+(1*8)=162
162 % 10 = 2
So 519148-48-2 is a valid CAS Registry Number.
519148-48-2Relevant articles and documents
Imidazopyridine compounds as 5-HT4 receptor modulators
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, (2008/06/13)
This invention provides a compound of the formula (I): 1or the pharmaceutically acceptable salts thereof wherein R1 is hydrogen, halo or alkyl; R2 and R3 are independently hydrogen, alkyl, alkenyl, alkynyl, aminoalkyl or
