5193-61-3

Basic information

• Product Name: 1-(2-bromobenzyl)-6-[(3-hydroxypropyl)amino]-3-methylpyrimidine-2,4(1H,3H)-dione
• CAS NO: 5193-61-3
• Molecular Formula: C₁₁H₇N₃OS
• Molecular Weight: 368.2257
• Mol File: 5193-61-3.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 520.1°C at 760 mmHg
• Flash Point: 268.4°C
• Density: 1.55g/cm³
• Vapor Pressure: 1.2E-11mmHg at 25°C
• Refractive Index: 1.654
• CAS DataBase Reference: 1-(2-bromobenzyl)-6-[(3-hydroxypropyl)amino]-3-methylpyrimidine-2,4(1H,3H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-bromobenzyl)-6-[(3-hydroxypropyl)amino]-3-methylpyrimidine-2,4(1H,3H)-dione(5193-61-3)
• EPA Substance Registry System: 1-(2-bromobenzyl)-6-[(3-hydroxypropyl)amino]-3-methylpyrimidine-2,4(1H,3H)-dione(5193-61-3)

Safety Data

• Hazardous Substances Data: 5193-61-3(Hazardous Substances Data)

Usage

Description

1-(2-bromobenzyl)-6-[(3-hydroxypropyl)amino]-3-methylpyrimidine-2,4(1H,3H)-dione is a chemical compound that belongs to the family of pyrimidines. It is a derivative of 1-(2-bromobenzyl)-3-methylpyrimidine-2,4(1H,3H)-dione, featuring a bromobenzyl group, a hydroxypropylamino group, and a methylpyrimidine-2,4(1H,3H)-dione group. 1-(2-bromobenzyl)-6-[(3-hydroxypropyl)amino]-3-methylpyrimidine-2,4(1H,3H)-dione may hold potential applications in the pharmaceutical industry, particularly in the development of drugs aimed at treating specific diseases or conditions. Further research and experimentation are necessary to determine its exact properties and possible uses.

Uses

Used in Pharmaceutical Industry:
1-(2-bromobenzyl)-6-[(3-hydroxypropyl)amino]-3-methylpyrimidine-2,4(1H,3H)-dione is used as a potential candidate for drug development due to its unique chemical structure and the possibility of targeting specific diseases or conditions. Its application in this industry is based on the need for novel compounds that can be tailored to interact with biological targets, potentially leading to the creation of new therapeutic agents.
Further research would be required to explore the compound's pharmacological properties, bioavailability, and potential side effects, as well as its ability to be synthesized on a larger scale for commercial use. 1-(2-bromobenzyl)-6-[(3-hydroxypropyl)amino]-3-methylpyrimidine-2,4(1H,3H)-dione's potential applications could range from treating various diseases to serving as a building block for other pharmaceutical compounds.

Upstream product

• 3364-80-5 1,3-thiazole-4-carbaldehyde 
• 28144-70-9 anthranilic acid amide 

Relevant articles and documents

Synthesis and biological evaluation of novel benzimidazole derivatives and analogs targeting the NLRP3 inflammasome

A series of benzo[d]imidazole analogues of thiabenzole were synthesized and their anti-inflammatory activities toward NLRP3 (nucleotide-binding domain leucine-rich repeat containing protein family, pyrin domain-containing 3, also known as cryopyrin or NALP3) inflammasome were evaluated in vitro. Two lead compounds, TBZ-09 and TBZ-21, were identified by anti-production of IL-1β. In the second round of biological evaluation, based on the lead, 34 more compounds were synthesized and their in vitro anti-inflammatory activities were investigated. Several compounds were identified as anti-inflammatory agents that can reduce IL-1β expression in a dose-dependent manner. A preliminary structure-activity relationship is also summarized here.