5194-49-0Relevant articles and documents
Iron-catalyzed stereoselective haloamidation of amide-tethered alkynes
Liu, Jin-Biao,Ren, Miaofeng,Lai, Xiaojing,Qiu, Guanyinsheng
supporting information, p. 4259 - 4262 (2021/05/05)
In this work, by usingN-methoxybenzamides as efficient acyl nitrene precursors, an iron-catalyzed formalcis-haloamidation of alkyne is reported. Without assistance of additives, the reaction worked well in the presence of 50 mol% FeCl3or FeBr3, leading to a series of chloro/bromo-containing isoindolin-5-ones with high efficiency and wide reaction scope. In the reaction, the iron-facilitated haloamidation proceeds through a halo anion-participating concerted [3+2] cyclization to release the final products. The key intermediate ferric acyl nitreneAis generatedin situfrom a formal removal of MeOH.
Ir(III)-Catalyzed Stereoselective Haloamidation of Alkynes Enabled by Ligand Participation
Hong, Seung Youn,Son, Junsoo,Kim, Dongwook,Chang, Sukbok
, p. 12359 - 12363 (2018/10/02)
Described herein is the application of a strategy of ligand participation for the Ir-catalyzed imido transfer into alkynes. On the basis of a stoichiometric [3 + 2] cycloaddition of Cp?Ir(III)(κ2-N,O-chelate) with alkynyl dioxazolone, a catalyt
