520-11-6

Basic information

• Product Name: 6-METHOXYLUTEOLIN
• Synonyms: EUPAFOLIN;6-METHOXYLUTEOLIN;NEPETIN;Eurafolin;Eupafloin 6-Methoxyluteolin;2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-6-methoxy-4H-1-benzopyran-4-one;2-(3-Hydroxy-4-hydroxyphenyl)-5,7-dihydroxy-6-methoxy-4H-1-benzopyran-4-one;NSC 122416
• CAS NO: 520-11-6
• Molecular Formula: C₁₆H₁₂O₇
• Molecular Weight: 316.26
• Product Categories: Tetra-substituted Flavones
• Mol File: 520-11-6.mol
• Article Data: 4

Chemical Properties

• Melting Point: 267°C
• Boiling Point: 659.058 °C at 760 mmHg
• Flash Point: 90℃
• Appearance: /
• Density: 1.605
• Vapor Pressure: 5.64E-18mmHg at 25°C
• Refractive Index: 1.727
• Storage Temp.: 2-8°C
• PKA: 6.48±0.40(Predicted)
• CAS DataBase Reference: 6-METHOXYLUTEOLIN(CAS DataBase Reference)
• NIST Chemistry Reference: 6-METHOXYLUTEOLIN(520-11-6)
• EPA Substance Registry System: 6-METHOXYLUTEOLIN(520-11-6)

Safety Data

• Hazardous Substances Data: 520-11-6(Hazardous Substances Data)

Usage

General Description

6-Methoxyluteolin is a natural flavonoid compound found in plants such as Desmodium gangeticum and Solidago canadensis. It is known for its potential anti-inflammatory, antioxidant, and anticancer properties. Studies have shown that 6-methoxyluteolin has the ability to inhibit the growth of certain cancer cells and induce apoptosis. It also exhibits anti-inflammatory effects by inhibiting the production of pro-inflammatory cytokines. Additionally, 6-methoxyluteolin has been found to have antioxidant activity, protecting cells from oxidative damage. These properties make 6-methoxyluteolin a promising candidate for the development of new therapeutic agents for treating cancer, inflammation, and oxidative stress-related diseases.

InChI:InChI=1/C16H12O7/c1-22-16-11(20)6-13-14(15(16)21)10(19)5-12(23-13)7-2-3-8(17)9(18)4-7/h2-6,17-18,20-21H,1H3

Upstream product

• 569-90-4 5,7,3',4'-tetrahydroxy-6-methoxyflavone-7-O-β-D-glucopyranoside 
• 88153-47-3 5,6-Dimethoxy-7,3',4'-trihydroxyflavone 

Downstream Products

• 18003-33-3 3',4',5,6,7-pentahydroxyflavone 
• 82657-12-3 C₂₂H₂₀O₁₃ 

Relevant articles and documents

New Flavonoids and Turkesterone-2-O-Cinnamate from Leaves of Rhaponticum uniflorum

Leaves of Rhaponticum uniflorum (L.) DC. (Asteraceae) afforded 46 compounds including seven new flavonoids that were identified using UV, IR, and NMR spectroscopy and mass spectrometry as 6-hydroxyluteolin-7-O-(2′-O-caffeoyl)-β-D-glucopyranoside (rhaunoside A, 1), 6-hydroxyluteolin-7-O-(6″-O-cinnamoyl)-β-D-glucopyranoside (rhaunoside B, 2), 6-hydroxyluteolin-4′-O-β-D-glucopyranoside (rhaunoside C, 3), nepetin-7-O-(6″-O-caffeoyl)-β-D-glucopyranoside (rhaunoside D, 4), nepetin-7-O-(6″-O-cinnamoyl)-β-D-glucopyranoside (rhaunoside E, 5), nepetin-3′-O-β-D-glucopyranoside (rhaunoside F, 6), and luteolin-7-O-(2″-O-caffeoyl)-β-D-glucopyranoside (rhaunoside G, 7) and the new ecdysteroid turkesterone-2-O-cinnamate (8).

Gastroprotective flavone/flavanone compounds with therapeutic effect on inflammatory bowel disease

PCT No. PCT/KR97/00144 Sec. 371 Date Jan. 14, 1999 Sec. 102(e) Date Jan. 14, 1999 PCT Filed Jul. 25, 1997 PCT Pub. No. WO98/04541 PCT Pub. Date Feb. 5, 1998The present invention relates to novel flavone/flavanone compounds or their pharmaceutically acceptable salts and process for preparation thereof for protecting gastrointestinal tracts against gastritis, ulcers and inflammatory bowel disease.