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520-63-8

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520-63-8 Usage

Uses

Heliotridine is a necine base alkaloid that exhibits hepatotoxic effects and also inhibits mitochondrial metabolism.

Check Digit Verification of cas no

The CAS Registry Mumber 520-63-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,2 and 0 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 520-63:
(5*5)+(4*2)+(3*0)+(2*6)+(1*3)=48
48 % 10 = 8
So 520-63-8 is a valid CAS Registry Number.
InChI:InChI=1/C8H13NO2/c10-5-6-1-3-9-4-2-7(11)8(6)9/h1,7-8,10-11H,2-5H2/t7-,8+/m0/s1

520-63-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 1H-Pyrrolizine-7-methanol,2,3,5,7a-tetrahydro- 1-hydroxy-,(1S,7aR)-

1.2 Other means of identification

Product number -
Other names (1S,7aR)-2,3,5,7a-Tetrahydro-1-hydroxy-1H-pyrrolizine-7-methanol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:520-63-8 SDS

520-63-8Relevant articles and documents

Expedient pyrrolizidine synthesis by propargylsilane addition to N-acyliminium ions followed by gold-catalyzed α-allenyl amide cyclization

Breman, Arjen C.,Dijkink, Jan,Van Maarseveen, Jan H.,Kinderman, Sape S.,Hiemstra, Henk

supporting information; experimental part, p. 6327 - 6330 (2009/12/24)

(Chemical Equation Presented) A reaction sequence, involving the addition of (substituted) propargylsilanes to lactam-derived N-acyliminium ions followed by gold-catalyzed cyclization of the resulting α-allenyl amide, is applied in expedient syntheses of

Isoechinatine, a pyrrolizidine alkaloid from Cynoglossum furcatum

Ravikumar,Lakshmanan

, p. 406 - 409 (2007/10/03)

The pyrrolizidine alkaloids of Cynoglossum furcatum have been isolated and characterized. They are isoechinatine 1, a new pyrrolizidine ester alkaloid, echinatine, neocoramandaline and a free necine heliotridine. Isoechinatine is formulated as 9-(O)-(+)-viridiflorylheliotridine. 3-Hydroxy 6-methylpyridine has also been isolated and characterized.

Intramolecular Allylstannane Cyclizations in Alkaloid Synthesis: Applications to Pyrrolizidine Alkaloids

Keck, Gary E.,Cressman, Erik N. K.,Enholm, Eric J.

, p. 4345 - 4349 (2007/10/02)

Syntheses of (+/-)-isoretronecanol, (+/-)-supinidine, (-)-dihydroxyheliotridane, and (+)-heliotridine are detailed.The key step in each case involves an intramolecular acyliminium ion cyclization onto a suitably positioned allylstannane for construction o

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