520-78-5Relevant articles and documents
Synthesis and DABCO-induced demethylation of 3-cyano-4-methoxy-2-pyridone derivatives
Li, Jing,Tan, Hong-Ru,An, Yu-Long,Shao, Zhi-Yu,Zhao, Sheng-Yin
, p. 486 - 496 (2020)
An efficient method for synthesis and demethylation of 3-cyano-4-methoxy-2-pyridone derivatives has been developed. DABCO-induced demethylation can lead to 3-cyano-4-hydroxy-2-pyridones in DMF at 90°C with high yield. The protocol is applicable for the synthesis of 3-cyano-4-hydroxy-2-pyridone derivatives. The method is simple, efficient, and practical.
Antimicrobial and antiquorum-sensing activity of Ricinus communis extracts and ricinine derivatives
El-Naggar, Mai H.,Elgaml, Abdelaziz,Abdel Bar, Fatma M.,Badria, Farid A.
, p. 1 - 7 (2018)
Ricinine (1), a known major alkaloid in Ricinus communis plant, was used as a starting compound for the synthesis of six ricinine derivatives; two new and four known compounds. The new derivatives; 3-amino-5-methyl-1H-pyrazolo[4,3-c]pyridin-4(5H)-one (2),