52006-62-9

Basic information

• Product Name: 1-Nitrobutane
• Synonyms: 1-NITROBUTANE
• CAS NO: 52006-62-9
• Molecular Formula: C4H9NO2
• Molecular Weight: 103.12
• Mol File: 52006-62-9.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-Nitrobutane(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Nitrobutane(52006-62-9)
• EPA Substance Registry System: 1-Nitrobutane(52006-62-9)

Safety Data

• Hazardous Substances Data: 52006-62-9(Hazardous Substances Data)

Usage

Description

1-Nitrobutane is an organic compound with the chemical formula C4H9NO2. It is a nitroalkane derivative, which consists of a butane chain with a nitro group (-NO2) attached to the first carbon atom. 1-Nitrobutane is known for its reactivity and is commonly used as an intermediate in the synthesis of various chemicals.

Uses

1. Used in Chemical Synthesis:
1-Nitrobutane is used as a synthetic intermediate for the preparation of various organic compounds. Its reactivity allows it to undergo a range of chemical reactions, making it a versatile building block in the chemical industry.
2. Used in Pharmaceutical Industry:
In the pharmaceutical industry, 1-Nitrobutane is used as a key component in the synthesis of certain drugs. Its ability to be reduced to form amines makes it a valuable precursor in the development of various medicinal compounds.
3. Used in Method for Preparing Amines:
1-Nitrobutane is used as a starting material in the method for preparing amines by reducing nitro compounds with pinacolborane under the catalysis of cyclic (alkyl) (amino) carbene chromium complex. This method is particularly useful for the synthesis of complex amine structures, which are important in the development of new pharmaceuticals and other specialty chemicals.

Synthesis Reference(s)

The Journal of Organic Chemistry, 35, p. 4229, 1970 DOI: 10.1021/jo00837a618Tetrahedron Letters, 27, p. 2335, 1986 DOI: 10.1016/S0040-4039(00)84522-0