52061-51-5 Usage
Description
4-(Benzyloxy)-N,N-dimethyl-indole-3-glyoxylamide is an off-white solid that serves as an intermediate in the preparation of various pharmaceutically active indole derivatives. It is a significant compound in the field of medicinal chemistry due to its potential applications in the development of new drugs.
Uses
Used in Pharmaceutical Industry:
4-(Benzyloxy)-N,N-dimethyl-indole-3-glyoxylamide is used as an intermediate for the synthesis of pharmaceutically active indole derivatives. Its role in the industry is crucial as it aids in the development of new drugs with potential therapeutic applications.
As an intermediate, 4-(Benzyloxy)-N,N-dimethyl-indole-3-glyoxylamide contributes to the creation of various indole-based compounds that can be utilized in the treatment of different medical conditions. 4-(Benzyloxy)-N,N-dimethyl-indole-3-glyoxylamide's chemical properties make it a valuable building block in the synthesis of these pharmaceutically relevant molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 52061-51-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,2,0,6 and 1 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 52061-51:
(7*5)+(6*2)+(5*0)+(4*6)+(3*1)+(2*5)+(1*1)=85
85 % 10 = 5
So 52061-51-5 is a valid CAS Registry Number.
52061-51-5Relevant articles and documents
3-(2-(AMINOETHYL)-INDOL-4-OL DERIVATIVES, METHODS OF PREPARATION THEREOF, AND THE USE AS 5-HT2 RECEPTOR MODULATORS
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Paragraph 0092-0093; 00234-00236, (2021/09/17)
A compound of Formula I, which possesses 5-HT2A and/or 5-HT2c selective receptor activity, but lacks at least some of the undesirable characteristics of 5-HT2B-agonist related activities, is disclosed. Methods of preparing said compo
Improvements to the synthesis of psilocybin and a facile method for preparing the O-acetyl prodrug of psilocin
Nichols, David E.,Frescas, Stewart
, p. 935 - 938 (2007/10/03)
An improved procedure to accomplish the O-phosphorylation of 4-hydroxy- N,N-dimethyltryptamine (psilocin 5) is reported that utilizes reaction between the O-lithium salt of 5 and tetra-O-benzylpyrophosphate. The O- benzyl groups were removed by catalytic hydrogenation over palladium on carbon to afford N,N-dimethyl-4-phosphoryloxytryptamine (psilocybin, 1). In view of difficulties encountered in the preparation of 1, it is suggested that 4-acetoxy-N,N-dimethyltryptamine (2) may be a useful alternative for pharmacological studies. The latter was obtained following catalytic O- debenzylation of 4-benzyloxy-N,N-dimethyltryptamine in the presence of acetic anhydride and sodium acetate.
