521-40-4

Post Buying Request

Basic information

Product Name: [S-(R*,R*)]-6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-hydroxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)phthalide
Synonyms: [S-(R*,R*)]-6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-hydroxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)phthalide;narcotoline;(3S)-6,7-Dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-4-hydroxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]isobenzofuran-1(3H)-one;Desmethylnarcotine;(3S)-3-[(5R)-4-hydroxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-6,7-dimethoxy-3H-2-benzofuran-1-one;(3S)-3-[(5R)-4-hydroxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-6,7-dimethoxy-3H-isobenzofuran-1-one
CAS NO:521-40-4
Molecular Formula: C₂₁H₂₁NO₇
Molecular Weight: 399.39394
EINECS: 208-313-6
Product Categories: N/A
Mol File: 521-40-4.mol
Article Data: 0

Chemical Properties

Melting Point: 202°
Boiling Point: 538°Cat760mmHg
Flash Point: 279.2°C
Appearance: /
Density: 1.403g/cm³
Vapor Pressure: 3.46E-12mmHg at 25°C
Refractive Index: 1.633
Storage Temp.: -20°C Freezer, Under inert atmosphere
Solubility: Chloroform (Slightly), Methanol (Slightly)
CAS DataBase Reference: [S-(R*,R*)]-6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-hydroxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)phthalide(CAS DataBase Reference)
NIST Chemistry Reference: [S-(R*,R*)]-6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-hydroxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)phthalide(521-40-4)
EPA Substance Registry System: [S-(R*,R*)]-6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-hydroxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)phthalide(521-40-4)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 521-40-4(Hazardous Substances Data)

Suppliers
Usage
SDS
Upstream product
Downstream Products

521-40-4 Suppliers

Recommended suppliersmore

Product
FOB Price
Min.Order
Supply Ability
Supplier
Contact Supplier

[S-(R*,R*)]-6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-hydroxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)phthalide
Cas No: 521-40-4
USD $ 3.0-3.0 / Kilogram
1 Kilogram
1-100 Metric Ton/Month
Dayang Chem (Hangzhou) Co.,Ltd.
Contact Supplier

[S-(R*,R*)]-6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-hydroxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)phthalide
Cas No: 521-40-4
No Data
No Data
No Data
Hangzhou Keyingchem Co.,Ltd
Contact Supplier

1(3H)-Isobenzofuranone,6,7-dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-4-hydroxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-,(3S)-
Cas No: 521-40-4
No Data
1 Gram
1 Metric Ton/Day
Shandong Mopai Biotechnology Co., LTD
Contact Supplier

1(3H)-Isobenzofuranone,6,7-dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-4-hydroxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-,(3S)-
Cas No: 521-40-4
No Data
No Data
No Data
Antimex Chemical Limied
Contact Supplier

Noscapine Impurity 6 (Narcotoline)
Cas No: 521-40-4
No Data
No Data
No Data
Topbatt Chemical Co., Ltd.
Contact Supplier

Noscapine Impurity 6 (Narcotoline)
Cas No: 521-40-4
No Data
No Data
No Data
Shenzhen Sumshine Biotech Co., Ltd.
Contact Supplier

Noscapine Impurity 6 (Narcotoline)
Cas No: 521-40-4
No Data
No Data
No Data
NovaChemistry
Contact Supplier

521-40-4 Usage

Description

Wrede has obtained this alkaloid from the seed capsules of Papaver somniferum. It crystallizes from aqueous MeOH in colourless rectangular rods and has [0:]5° - 189° (CHCI3) and + 5.8° (c 0.1 NiHCI). One phenolic hydroxyl group is present in the molecule and the base forms the O-acetate, m.p. 208-9°C, giving a hydro_x0002_chloride as the monohydrate, m.p. 230-3°C (dry); [0:]5° + 94.8° (H 20). The acid tartrate forms colourless needles which, decompose at 190-205°C and the picrolonate has m.p. 202-3°C. On treatment with CH2N2, the alkaloid gives Narcotine (q.v.).

Uses

Desmethylnarcotine is an impurity of Narcotoline an opiate alkaloid and a structure analogue of Nascapine (N882000), an antitussive agent. Noscapine (N882000) metabolite.

References

Wrede., r;hem. Zentr., I, 2611 (1937)Wrede., ibid, II, 863 (1938)

Check Digit Verification of cas no

The CAS Registry Mumber 521-40-4 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,2 and 1 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 521-40:
(5*5)+(4*2)+(3*1)+(2*4)+(1*0)=44
44 % 10 = 4
So 521-40-4 is a valid CAS Registry Number.

InChI:InChI=1/C21H21NO7/c1-22-7-6-10-8-13-20(28-9-27-13)17(23)14(10)16(22)18-11-4-5-12(25-2)19(26-3)15(11)21(24)29-18/h4-5,8,16,18,23H,6-7,9H2,1-3H3/t16-,18+/m1/s1

521-40-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name	(3S)-3-[(5R)-4-hydroxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-6,7-dimethoxy-3H-2-benzofuran-1-one

1.2 Other means of identification

Product number	-
Other names	Narcotoline

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:521-40-4 SDS

521-40-4Upstream product

521-40-4Downstream Products

Post a RFQ

Cas No.:

Product Name:

Quantity:

Email:

Company name:

Valid Period:

Detailed Requirements:

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

What can I do for you?
Get Best Price

Get Best Price for 521-40-4