52107-78-5 Usage
Description
1-(2-iodo-6-methylphenyl)ethanone, with the molecular formula C9H9IO, is a chemical compound that exists as a pale yellow to brown liquid. It is utilized in various fields due to its versatile reactivity and serves as a reagent and intermediate in organic synthesis and medicinal chemistry.
Uses
Used in Pharmaceutical and Agrochemical Industries:
1-(2-iodo-6-methylphenyl)ethanone is used as a key intermediate for the synthesis of various pharmaceuticals and agrochemicals, contributing to the development of new drugs and agricultural products.
Used in Fragrance and Flavor Industry:
1-(2-iodo-6-methylphenyl)ethanone is employed as a building block in the production of fragrances and flavors, enhancing the scent and taste profiles of different products.
Used in Specialty Polymers and Materials Industry:
1-(2-iodo-6-methylphenyl)ethanone is used as a component in the synthesis of specialty polymers and materials, contributing to the creation of unique materials with specific properties for various applications.
Safety Precautions:
It is crucial to handle 1-(2-iodo-6-methylphenyl)ethanone with care, as it can cause irritation to the skin, eyes, and respiratory system. It should only be used in well-ventilated areas by trained professionals to ensure safety during its application.
Check Digit Verification of cas no
The CAS Registry Mumber 52107-78-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,2,1,0 and 7 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 52107-78:
(7*5)+(6*2)+(5*1)+(4*0)+(3*7)+(2*7)+(1*8)=95
95 % 10 = 5
So 52107-78-5 is a valid CAS Registry Number.
52107-78-5Relevant articles and documents
Palladium-catalyzed: Ortho -halogen-induced deoxygenative approach of alkyl aryl ketones to 2-vinylbenzoic acids
Ram, Shankar,Sharma, Ajay Kumar,Chauhan, Arvind Singh,Das, Pralay
supporting information, p. 10674 - 10677 (2020/10/02)
The 2-vinylbenzoic acids have wide applications in the field of polymer chemistry and are key precursors for the synthesis of important bioactive molecules. Herein, an ortho-halogen-induced deoxygenative approach for the generation of 2-vinylbenzoic acids from alkyl aryl ketones by palladium catalysis is discovered and explored. This approach requires no base or stoichiometric additives and can be carried out through a simple one-step process. Furthermore, the present reaction is scalable up to one-gram scale. The commercially available palladium on carbon (5 wt%) was used as a heterogeneous catalyst and showed excellent recyclability (5 times) without significant loss in catalytic activity. Pleasingly, under our optimized conditions, the alpha alkyl substituted 2-iodoacetophenones exhibit good diastereoselectivity and predominantly (E)-2-vinylbenzoic acids were obtained with good to excellent yields.
