521274-48-6

Basic information

• Product Name: (1S,3R)-3-{(1Z,3Z,5R,7R,8R,9E)-8-(2-{[(allyloxyl)carbonyl]amino}ethyl)-7-{[bis(allyloxy)phosphoryl]oxy}-10-[(2S,3S)-3-ethyl-6-oxo-3,6-dihydro-2H-pyran-2-yl]-5-hydroxy-8-[(trimethylsilyl)oxy]deca-1,3,9-trienyl}cyclohexyl (6S)-6-methyloctanoate
• Synonyms: (1S,3R)-3-{(1Z,3Z,5R,7R,8R,9E)-8-(2-{[(allyloxyl)carbonyl]amino}ethyl)-7-{[bis(allyloxy)phosphoryl]oxy}-10-[(2S,3S)-3-ethyl-6-oxo-3,6-dihydro-2H-pyran-2-yl]-5-hydroxy-8-[(trimethylsilyl)oxy]deca-1,3,9-trienyl}cyclohexyl (6S)-6-methyloctanoate
• CAS NO: 521274-48-6
• Molecular Weight: 906.179
• Mol File: 521274-48-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (1S,3R)-3-{(1Z,3Z,5R,7R,8R,9E)-8-(2-{[(allyloxyl)carbonyl]amino}ethyl)-7-{[bis(allyloxy)phosphoryl]oxy}-10-[(2S,3S)-3-ethyl-6-oxo-3,6-dihydro-2H-pyran-2-yl]-5-hydroxy-8-[(trimethylsilyl)oxy]deca-1,3,9-trienyl}cyclohexyl (6S)-6-methyloctanoate(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,3R)-3-{(1Z,3Z,5R,7R,8R,9E)-8-(2-{[(allyloxyl)carbonyl]amino}ethyl)-7-{[bis(allyloxy)phosphoryl]oxy}-10-[(2S,3S)-3-ethyl-6-oxo-3,6-dihydro-2H-pyran-2-yl]-5-hydroxy-8-[(trimethylsilyl)oxy]deca-1,3,9-trienyl}cyclohexyl (6S)-6-methyloctanoate(521274-48-6)
• EPA Substance Registry System: (1S,3R)-3-{(1Z,3Z,5R,7R,8R,9E)-8-(2-{[(allyloxyl)carbonyl]amino}ethyl)-7-{[bis(allyloxy)phosphoryl]oxy}-10-[(2S,3S)-3-ethyl-6-oxo-3,6-dihydro-2H-pyran-2-yl]-5-hydroxy-8-[(trimethylsilyl)oxy]deca-1,3,9-trienyl}cyclohexyl (6S)-6-methyloctanoate(521274-48-6)

Safety Data

• Hazardous Substances Data: 521274-48-6(Hazardous Substances Data)

Upstream product

• 467234-68-0 (S)-6-Methyl-octanoic acid (1S,3R)-3-[(1Z,3Z,9E)-(5R,7R,8R)-8-(2-allyloxycarbonylamino-ethyl)-5-(2-chloro-acetoxy)-10-((2S,3S)-3-ethyl-6-oxo-3,6-dihydro-2H-pyran-2-yl)-7-hydroxy-8-trimethylsilanyloxy-deca-1,3,9-trienyl]-cyclohexyl ester 
• 467234-67-9 (S)-6-Methyl-octanoic acid (1S,3R)-3-[(1Z,3Z,9E)-(5R,7R,8R)-8-(2-allyloxycarbonylamino-ethyl)-10-((2S,3S)-3-ethyl-6-oxo-3,6-dihydro-2H-pyran-2-yl)-5,7-dihydroxy-8-trimethylsilanyloxy-deca-1,3,9-trienyl]-cyclohexyl ester 
• 467234-65-7 (S)-6-Methyl-octanoic acid (1S,3R)-3-((1Z,3Z)-4-{(4R,6R)-6-[(E)-(R)-1-(2-allyloxycarbonylamino-ethyl)-3-((2S,3S)-3-ethyl-6-oxo-3,6-dihydro-2H-pyran-2-yl)-1-hydroxy-allyl]-2,2-dimethyl-[1,3]dioxan-4-yl}-buta-1,3-dienyl)-cyclohexyl ester 
• 467234-66-8 (S)-6-Methyl-octanoic acid (1S,3R)-3-[(1Z,3Z,9E)-(5R,7R,8R)-8-(2-allyloxycarbonylamino-ethyl)-10-((2S,3S)-3-ethyl-6-oxo-3,6-dihydro-2H-pyran-2-yl)-5,7,8-trihydroxy-deca-1,3,9-trienyl]-cyclohexyl ester 
• 685530-39-6 [(7Z,9Z)-(3R,4R,6R)-3-[(E)-2-((2S,3S)-3-Ethyl-6-oxo-3,6-dihydro-2H-pyran-2-yl)-vinyl]-3,6-dihydroxy-10-((1R,3S)-3-hydroxy-cyclohexyl)-4-phosphonooxy-deca-7,9-dienyl]-carbamic acid allyl ester 
• 467234-63-5 [(7Z,9Z)-(3R,4R,6R)-3-[(E)-2-((2S,3S)-3-Ethyl-6-oxo-3,6-dihydro-2H-pyran-2-yl)-vinyl]-3,4,6-trihydroxy-10-((1R,3S)-3-hydroxy-cyclohexyl)-deca-7,9-dienyl]-carbamic acid allyl ester 
• 467234-64-6 ((E)-(R)-5-((2S,3S)-3-Ethyl-6-oxo-3,6-dihydro-2H-pyran-2-yl)-3-hydroxy-3-{(4R,6R)-6-[(1Z,3Z)-4-((1R,3S)-3-hydroxy-cyclohexyl)-buta-1,3-dienyl]-2,2-dimethyl-[1,3]dioxan-4-yl}-pent-4-enyl)-carbamic acid allyl ester 
• 521274-40-8 4-{(2R,4R,5R)-5-allyl-4-[(1E)-3-hydroxyprop-1-enyl]-4-[2-(trityloxy)ethyl]-[1,3]dioxolan-2-yl}phenol 
• 126429-21-8 diallyl diisopropylphosphoramidite 
• 521274-37-3 6-methyl-octanoic acid 3-[8-(2-allyloxycarbonylamino-ethyl)-7-(bis-allyloxy-phosphoryloxy)-10-(3-ethyl-6-oxo-3,6-dihydro-2H-pyran-2-yl)-5-phenoxyacetoxy-8-trimethylsilanyloxy-deca-1,3,9-trienyl]-cyclohexyl ester 
• 467234-69-1 6-methyl-octanoic acid 3-[8-(2-allyloxycarbonylamino-ethyl)-7-(bis-allyloxy-phosphoryloxy)-5-chloroacetoxy-10-(3-ethyl-6-oxo-3,6-dihydro-2H-pyran-2-yl)-8-trimethylsilanyloxy-deca-1,3,9-trienyl]-cyclohexyl ester 
• 521274-34-0 phenoxy-acetic acid 1-[2-[4-(tert-butyl-dimethyl-silanyloxy)-phenyl]-5-[2-(3-ethyl-6-oxo-3,6-dihydro-2H-pyran-2-yl)-vinyl]-5-(2-trityloxy-ethyl)-[1,3]dioxolan-4-ylmethyl]-5-[3-(4-methoxy-phenoxymethoxy)-cyclohexyl]-penta-2,4-dienyl ester 
• 521274-30-6 [(2R,4R,5R)-2-[4-(tert-Butyl-dimethyl-silanyloxy)-phenyl]-5-[(E)-2-((2S,3S)-3-ethyl-6-oxo-3,6-dihydro-2H-pyran-2-yl)-vinyl]-5-(2-trityloxy-ethyl)-[1,3]dioxolan-4-yl]-acetaldehyde 
• 521274-26-0 (2E)-3-{(2R,4R,5R)-5-allyl-2-(4-{[tert-butyl(dimethyl)silyl]oxy}phenyl)-4-[2-(trityloxy)ethyl]-[1,3]dioxolan-4-yl}acrylaldehyde 

Downstream Products

• 145142-82-1 leustroducsin B 

Relevant articles and documents

Total synthesis of leustroducsin B

A convergent total synthesis of leustroducsin B (1), which is known to exhibit a variety of biological activities, was successfully carried out. Notable features of our synthesis include construction of the C8 stereocenter by lipase-mediated desymmetrizat