52129-03-0

Basic information

• Product Name: 2,2-DIMETHYL-4-PHENYL-1,3-DIOXOLANE
• Synonyms: 2,2-DIMETHYL-4-PHENYL-1,3-DIOXOLANE
• CAS NO: 52129-03-0
• Molecular Formula: C₁₁H₁₄O₂
• Molecular Weight: 178.23
• Mol File: 52129-03-0.mol
• Article Data: 37

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,2-DIMETHYL-4-PHENYL-1,3-DIOXOLANE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-DIMETHYL-4-PHENYL-1,3-DIOXOLANE(52129-03-0)
• EPA Substance Registry System: 2,2-DIMETHYL-4-PHENYL-1,3-DIOXOLANE(52129-03-0)

Safety Data

• Hazardous Substances Data: 52129-03-0(Hazardous Substances Data)

Usage

General Description

2,2-Dimethyl-4-phenyl-1,3-dioxolane is a chemical compound with the molecular formula C11H14O2. It is a colorless liquid with a molecular weight of 178.23 g/mol. This chemical is frequently used as a solvent and in the manufacturing of pharmaceuticals and other organic compounds. It has a sweet, floral odor and is flammable in nature. 2,2-Dimethyl-4-phenyl-1,3-dioxolane is also known by other names such as 2,2-Dimethyl-4-phenyl-1,3-dioxacyclopentane and 2,2-dimethyl-4-phenyl-1,3-dioxane. It is important to handle this compound with care as it can cause skin and eye irritation, and inhalation may lead to respiratory discomfort. Additionally, it should be stored in a cool, dry place and away from sources of ignition.

Upstream product

• 96-09-3 styrene oxide 
• 109-63-7 trifluoroborane diethyl ether 
• 67-64-1 acetone 
• 18604-19-8 11,2:4,6-di-O-isopropylidene-α-L-sorbofuranose 
• 16713-80-7 3-O-acetyl-1,2:5,6-Di-O-isopropylidene-α-D-glucofuranose 
• 100-42-5 styrene 
• 93-56-1 phenylethane 1,2-diol 
• 20881-04-3 1,2:3,5-di-O-isopropylidene-D-xylofuranose 
• 14131-84-1 2,3:5,6-di-O-isopropylidene-α-D-mannofuranose 
• 108-22-5 Isopropenyl acetate 
• 77-76-9 2,2-dimethoxy-propane 

Downstream Products

• 75567-13-4 2-(tert-butoxy)-2-phenylethanol 
• 138344-76-0 1-Acetoxy-2-isopropoxy-1-phenylethane 
• 138344-72-6 2-Acetoxy-1-isopropoxy-1-phenylethane 
• 89101-31-5 2-isopropoxy-2-phenylethanol 
• 3578-32-3 2-isopropoxy-1-phenylethanol 
• 93-56-1 phenylethane 1,2-diol 
• 145125-20-8 α-phenyl-α-tert-butyloxyacetaldehyde 
• 98-86-2 acetophenone 

Relevant articles and documents

Ultrasound Assisted the Synthesis of 1,3-Dioxolane Derivatives from the Reaction of Epoxides or 1,2-Diols with Various Ketones Using Graphene Oxide Catalyst

Abstract: The main objective of this study concerns the sonochemical synthesis of 1,3-dioxolane derivatives using graphene oxide catalyst by applying two methods. In the first method, we described the synthesis of 1,3-dioxolane by ring-opening of epoxides in the presence of ketones catalyzed by graphene oxide (GO) under ultrasonic irradiation. In the second sonochemical procedure, we described the synthesis of 1,3-dioxolane derivatives by the reaction of 1,2-diols with ketones using same GO catalyst. Mild reaction conditions, high yields, short reaction times, reusability of catalyst and easy isolation of the products make the developed methods very useful. Graphic Abstract: [Figure not available: see fulltext.]

Convenient method for the transformation of epoxide to aldehyde and acetonide mediated by Cr-PLM

Chromium-pillared montmorillonite (Cr-PLM) could be synthesized and efficiently utilized for styrene oxide transformations. The target aldehyde product could be quantitatively achieved from the isomerization of styrene oxide by using 10 wt% of Cr-PLM under reflux temperature for 15 min. The acetonide product could be achieved in excellent yield from the reaction of styrene oxide and acetone by using 10 wt% of Cr-PLM under room temperature for 20 min. The catalyst could be recovered and reused at least five times without loss of activity.

Iron oxide-pillared clay catalyzed the synthesis of acetonides from epoxides

FeOx-pillared clays (FeOx-pillared bentonite, FeOx-pillared hectorite and FeOx-pillared taeniolite) were synthesized by the intercalation of FeCl3 into clay interlayers and calcination. The synthesize