52134-45-9

Basic information

• Product Name: Carbamic acid, [2-(oxiranylmethoxy)phenyl]-, ethyl ester
• CAS NO: 52134-45-9
• Molecular Formula: C12H15NO4
• Molecular Weight: 237.255
• Mol File: 52134-45-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Carbamic acid, [2-(oxiranylmethoxy)phenyl]-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [2-(oxiranylmethoxy)phenyl]-, ethyl ester(52134-45-9)
• EPA Substance Registry System: Carbamic acid, [2-(oxiranylmethoxy)phenyl]-, ethyl ester(52134-45-9)

Safety Data

• Hazardous Substances Data: 52134-45-9(Hazardous Substances Data)

Upstream product

• 56836-51-2 ethyl (2-hydroxyphenyl)carbamate 
• 106-89-8 epichlorohydrin 
• 95-55-6 2-amino-phenol 

Downstream Products

• 83855-47-4 [2-(2-Hydroxy-3-isopropylamino-propoxy)-phenyl]-carbamic acid ethyl ester 
• 52134-40-4 [2-(3-tert-Butylamino-2-hydroxy-propoxy)-phenyl]-carbamic acid ethyl ester 

Relevant articles and documents

Synthesis and structure-activity relationships of new β-adrenoreceptor antagonists. Evidence for the electrostatic requirements for β-adrenoreceptor antagonists

A series of mono- and disubstituted phenoxypropanolamines, structurally related to practolol and acebutolol, has been synthesized and tested for β-adrenoreceptor blocking activity. Structure-activity relationships are discussed. The reasons for the lack of activity of compounds 3n and 4n have also been examined. The results suggest that the negative electrostatic potential above the phenyl ring of phenoxypropanolamines is essential for binding activity and point to the presence of an electropositive residue in the β-adrenoreceptor binding site.